Potential of lymph-node ratio as a prognostic factor for patients with oral squamous cell carcinoma

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dc.contributor.authorTomo, Saygo [UNESP]
dc.contributor.authorAraújo, Winicius Arildo Ferreira [UNESP]
dc.contributor.authorde Castro, Tamara Fernandes [UNESP]
dc.contributor.authorNeto, Sebastião Conrado [UNESP]
dc.contributor.authorCollado, Francisco Urbano [UNESP]
dc.contributor.authorBiasoli, Éder Ricardo [UNESP]
dc.contributor.authorBernabé, Daniel Galera [UNESP]
dc.contributor.authorMiyahara, Glauco Issamu [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-03-01T21:09:36Z
dc.date.available2023-03-01T21:09:36Z
dc.date.issued2022-01-01
dc.description.abstractBackground: To analyze the influence of the lymph node ratio (LNR) in survival of patients with OSCC Methods: Clinicopathologic data from patients with OSCC who were treated with curative surgery and neck dissection (ND) with or without adjuvant therapies from 1991 to 2015 was retrospectively assessed. The impact of LNR and other variables on overall survival (OS) and disease-free survival (DFS) was analyzed in univariate and multivariate analyses. Results: One hundred nineteen patients were included. In the univariate analysis the LNR had a significant impact on OS (p = 0.01) and DFS (p = 0.01). In the multivariate analysis, the LNR was the only significantly independent factor influencing in the OS (p = 0.03). The adjuvant therapies did not influence on the OS (p = 0.42) and DFS (p = 0.10). Conclusions: The LNR is an independent prognostic factor in patients with OSCC. The LNR alone is not recommended to indicate the performance of adjuvant therapies.en
dc.description.affiliationOral Oncology Center São Paulo State University (UNESP) School of Dentistry, OJosé Bonifácio Street, 1193
dc.description.affiliationDepartment of Diagnosis and Surgery São Paulo State University (UNESP) School of Dentistry
dc.description.affiliationUnespOral Oncology Center São Paulo State University (UNESP) School of Dentistry, OJosé Bonifácio Street, 1193
dc.description.affiliationUnespDepartment of Diagnosis and Surgery São Paulo State University (UNESP) School of Dentistry
dc.identifierhttp://dx.doi.org/10.1016/j.jormas.2022.07.013
dc.identifier.citationJournal of Stomatology, Oral and Maxillofacial Surgery.
dc.identifier.doi10.1016/j.jormas.2022.07.013
dc.identifier.issn2468-7855
dc.identifier.scopus2-s2.0-85136550799
dc.identifier.urihttp://hdl.handle.net/11449/241552
dc.language.isoeng
dc.relation.ispartofJournal of Stomatology, Oral and Maxillofacial Surgery
dc.sourceScopus
dc.subjectCervical lymph node metastasis
dc.subjectLymph node ratio
dc.subjectOral cancer
dc.subjectOral squamous cell carcinoma
dc.subjectPrognostic factors
dc.titlePotential of lymph-node ratio as a prognostic factor for patients with oral squamous cell carcinomaen
dc.typeArtigo
unesp.author.orcid0000-0002-2295-7968 0000-0002-2295-7968[1]

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Araçatuba - COB - Centro de Oncologia Bucal