On non-linear dynamics and an optimal control synthesis of the action potential of membranes (ideal and non-ideal cases) of the Hodgkin-Huxley (HH) mathematical model
Nenhuma Miniatura disponível
Data
2009-02-28
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Pergamon-Elsevier B.V. Ltd
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
In this paper, we have studied the plasmatic membrane behavior using all electric circuit developed by Hodgkin and Huxley in 1952 and have dealt with the variation of the amount of time related to the potassium and sodium conductances in the squid axon. They developed differential equations for the propagation of electric signals; the dynamics of the Hodgkin-Huxley model have been extensively studied both from the view point of its their biological implications and as a test bed for numerical methods, which can be applied to more complex models. Recently, all irregular chaotic movement of the action potential of the membrane was observed for a number of techniques of control with the objective to stabilize the variation of this potential. This paper analyzes the non-linear dynamics of the Hodgkin-Huxley mathematical model, and we present some modifications in the governing equations of the system in order to make it a non-ideal one (taking into account that the energy source has a limited power supply). We also developed an optimal linear control design for the action potential of membranes. Here, we discuss the conditions that allow the use of control linear feedback for this kind of non-linear system.
Descrição
Palavras-chave
Idioma
Inglês
Como citar
Chaos Solitons & Fractals. Oxford: Pergamon-Elsevier B.V. Ltd, v. 39, n. 4, p. 1651-1666, 2009.