miRNApath: A database of miRNAs, target genes and metabolic pathways

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dc.contributor.authorChiromatzo, A. O.
dc.contributor.authorOliveira, T. Y. K.
dc.contributor.authorPereira, G.
dc.contributor.authorCosta, A. Y.
dc.contributor.authorMontesco, C. A. E.
dc.contributor.authorGras, D. E.
dc.contributor.authorYosetake, F.
dc.contributor.authorVilar, J. B.
dc.contributor.authorCervato, M.
dc.contributor.authorPrado, P. R. R.
dc.contributor.authorCardenas, R. G. C. C. L.
dc.contributor.authorCerri, R. [UNESP]
dc.contributor.authorBorges, R. L.
dc.contributor.authorLemos, R. N.
dc.contributor.authorAlvarenga, S. M.
dc.contributor.authorPerallis, V. R. C. [UNESP]
dc.contributor.authorPinheiro, D. G.
dc.contributor.authorSilva, I. T.
dc.contributor.authorBrandão, R. M.
dc.contributor.authorCunha, M. A. V.
dc.contributor.authorGiuliatti, S.
dc.contributor.authorSilva, W. A.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade de Ribeirão Preto (UNAERP)
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Viçosa (UFV)
dc.date.accessioned2014-05-27T11:22:45Z
dc.date.available2014-05-27T11:22:45Z
dc.date.issued2007-12-28
dc.description.abstractMicroRNAs (miRNAs) are small non-coding RNAs that regulate target gene expression and hence play important roles in metabolic pathways. Recent studies have evidenced the interrelation of miRNAs with cell proliferation, differentiation, development, and diseases. Since they are involved in gene regulation, they are intrinsically related to metabolic pathways. This leads to questions that are particularly interesting for investigating medical and laboratorial applications. We developed an miRNApath online database that uses miRNA target genes to link miRNAs to metabolic pathways. Currently, databases about miRNA target genes (DIANA miRGen), genomic maps (miRNAMap) and sequences (miRBase) do not provide such correlations. Additionally, miRNApath offers five search services and a download area. For each search, there is a specific type of input, which can be a list of target genes, miRNAs, or metabolic pathways, which results in different views, depending upon the input data, concerning relationships between the target genes, miRNAs and metabolic pathways. There are also internal links that lead to a deeper analysis and cross-links to other databases with more detailed information. miRNApath is being continually updated and is available at http://lgmb.fmrp.usp.br/mirnapath. ©FUNPEC-RP.en
dc.description.affiliationDepartamento de Genética Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP
dc.description.affiliationDepartamento de Bioinformática Universidade de Ribeirão Preto, Ribeirão Preto, SP
dc.description.affiliationDepartamento de Física e Matemática Universidade de São Paulo, Ribeirão Preto, SP
dc.description.affiliationDepartamento de Informática Biomédica Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP
dc.description.affiliationDepartamento de Biologia Geral Instituto de Ciências Biológicas Universidade Federal de Goiás, Goiânia, GO
dc.description.affiliationDepartamento de Estatística, Matemática Aplicada e Computação Instituto de Geociências e Ciências Exatas Universidade Estadual Paulista, Rio Claro, SP
dc.description.affiliationInstituto de Biotecnologia Aplicada À Agricultura Universidade Federal de Viçosa, Viçosa, MG
dc.description.affiliationUnespDepartamento de Estatística, Matemática Aplicada e Computação Instituto de Geociências e Ciências Exatas Universidade Estadual Paulista, Rio Claro, SP
dc.format.extent859-865
dc.identifierhttp://www.geneticsmr.com//year2007/vol6-4/pdf/xm0008.pdf
dc.identifier.citationGenetics and Molecular Research, v. 6, n. 4, p. 859-865, 2007.
dc.identifier.file2-s2.0-37349008944.pdf
dc.identifier.issn1676-5680
dc.identifier.scopus2-s2.0-37349008944
dc.identifier.urihttp://hdl.handle.net/11449/70220
dc.identifier.wosWOS:000251697000009
dc.language.isoeng
dc.relation.ispartofGenetics and Molecular Research
dc.relation.ispartofsjr0,439
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDatabase
dc.subjectInteraction
dc.subjectInvestigation
dc.subjectMetabolic pathways
dc.subjectMicroRNA
dc.subjectTarget genes
dc.subjectmicroRNA
dc.subjectRNA
dc.subjectcell differentiation
dc.subjectcell maturation
dc.subjectcell proliferation
dc.subjectconference paper
dc.subjectcorrelation analysis
dc.subjectcross linking
dc.subjectgene control
dc.subjectgene expression
dc.subjectgene sequence
dc.subjectgenomics
dc.subjectlaboratory
dc.subjectmetabolism
dc.subjectAnimals
dc.subjectComputational Biology
dc.subjectDatabases, Nucleic Acid
dc.subjectHumans
dc.subjectMetabolic Networks and Pathways
dc.subjectMicroRNAs
dc.subjectSoftware
dc.titlemiRNApath: A database of miRNAs, target genes and metabolic pathwaysen
dc.typeTrabalho apresentado em evento
dcterms.licensehttp://www.geneticsmr.com/node/5
unesp.author.orcid0000-0001-9364-2886[22]
unesp.author.orcid0000-0002-2582-1695[12]
unesp.author.orcid0000-0002-7520-6420[21]
unesp.author.orcid0000-0002-4687-1499[22]
unesp.author.orcid0000-0001-7062-5936[17]
unesp.author.orcid0000-0002-2654-0879[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Geociências e Ciências Exatas, Rio Claropt

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Artigos - Estatistica, Matemática Aplicada e Computação - IGCE