Chronic reparative changes in medium-sized vessels in a case of primary cutaneous anaplastic large-cell lymphoma with angioinvasive features and cytotoxic phenotype: new histopathological findings in line with indolent clinical behavior

Nenhuma Miniatura disponível

Data

2015-05-01

Autores

Macarenco, Ricardo S.
Oliveira, Deilson Elgui de [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Lippincott Williams &wilkins

Resumo

Angioinvasion/angiodestruction has been reported in a small subset of primary cutaneous anaplastic large-cell lymphomas (PCALCL). Recently, PCALCL with angioinvasive features and cytotoxic phenotype has been characterized as a variant associated with good clinical outcomes despite worrisome histopathologic features. We report a case of PCALCL with angioinvasive features and cytotoxic phenotype associated with reparative changes on the wall of medium-sized vessels involved by the neoplasm, including intimal fibroblastic proliferation and luminal obliteration. This vascular pattern, although previously unreported in PCALCL, is in accordance with the indolent behavior observed in this entity and provides a further link with lymphomatoid papulosis type E.

Descrição

Palavras-chave

Primary cutaneous anaplastic large-cell lymphoma, CD30(+) lymphoproliferative disorder, Angiocentric lymphoma, Angioinvasive lymphoma, Cutaneous lymphoma, Cytotoxic phenotype, Endarteritis obliterans, Pseudovasculitis, Angiodestructive, Angioinvasive, Muscular vessels, Medium-sized vessels

Como citar

American Journal Of Dermatopathology. Philadelphia: Lippincott Williams &wilkins, v. 37, n. 5, p. 53-56, 2015.