Stroke as the First Clinical Manifestation of Takayasu's Arteritis

dc.contributor.authorCaldeira Pereira, Vanessa
dc.contributor.authorFreitas, Carlos Clayton Macêdo de [UNESP]
dc.contributor.authorLuvizutto, Gustavo José
dc.contributor.authorLima Sobreira, Marcone
dc.contributor.authorEscobar Bueno Peixoto, Daniel
dc.contributor.authorDo Nascimento MagalhÃes, Inaldo
dc.contributor.authorBazan, Rodrigo
dc.contributor.authorPereira Braga, Gabriel
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.abstractTakayasu's arteritis is a chronic inflammatory disease, and neurological symptoms occur in 50% of cases, most commonly including headache, dizziness, visual disturbances, convulsive crisis, transient ischemic attack, stroke and posterior reversible encephalopathy syndrome. The aim of this study was to report the case of a young Brazilian female with a focal neurological deficit. She presented with asymmetry of brachial and radial pulses, aphasia, dysarthria and right hemiplegia. Stroke was investigated extensively in this young patient. Only nonspecific inflammatory markers such as velocity of hemosedimentation and C-reactive protein were elevated. During hospitalization, clinical treatment was performed with pulse therapy showing improvement in neurological recuperation on subsequent days. In the chronic phase, the patient was submitted to medicated angioplasty of the brachiocephalic trunk with paclitaxel, with significant improvement of the stenosis. At the 6-month follow-up, the neurological exam presented mild dysarthria, faciobrachial predominant disproportionate hemiparesis, an NIHSS score of 4 and a modified Rankin Scale score of 3 (moderate incapacity). In conclusion, Takayasu's arteritis must be recognized as a potential cause of ischemic stroke in young females.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina de Botucatu, Botucatu, Rubiao Junior, Rubião Junior, CEP 18600000, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina de Botucatu, Botucatu, Rubiao Junior, Rubião Junior, CEP 18600000, SP, Brasil
dc.identifier.citationCase Reports in Neurology, v. 6, n. 3, p. 271-274, 2014.
dc.relation.ispartofCase Reports in Neurology
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.titleStroke as the First Clinical Manifestation of Takayasu's Arteritisen
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt