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Use of surgery and carboplatin in feline malignant mammary gland neoplasms with advanced clinical staging

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dc.contributor.authorDe Campos, Cecilia Bonolo [UNESP]
dc.contributor.authorNunes, Fernanda Camargo
dc.contributor.authorLavalle, Gleidice Eunice
dc.contributor.authorCassali, Geovanni Dantas [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionLaboratory of Comparative Pathology, Department of General Pathology, Biological Science Institute (ICB)
dc.contributor.institutionVeterinary Hospital, Veterinary School, Department of Veterinary Clinic and Surgery
dc.date.accessioned2018-12-11T16:38:06Z
dc.date.available2018-12-11T16:38:06Z
dc.date.issued2014-01-01
dc.description.abstractBackground/Aim: Feline mammary carcinomas (FMCs) are characterized by poor prognosis and little progress has been made in extending patient survival. The aim of the study was to compare overall survival periods of FMCs submitted to different treatment protocols, including surgery and adjuvant chemotherapy. Materials and Methods: Analysis of conventional surgical excision alone or in association with adjuvant chemotherapy with carboplatin in sixteen cats diagnosed with stage III and grade II or III FMCs was performed. Results: Patients treated with surgery and chemotherapy presented a longer overall survival (OS) than those treated only with surgery, however, no statistical difference was observed when comparing both treatments (p=0.883). Conclusion: Therapeutic benefit of carboplatin remains invalidated for FMCs and further investigation regarding adjuvant therapies are warranted. Surgery remains as the gold treatment in FMCs.en
dc.description.affiliationPostgraduate Program of Veterinary Medicine, School of Agricultural and Veterinary Sciences of the Sao Paulo State University (FCAV/UNESP), Jaboticabal Campus
dc.description.affiliationLaboratory of Comparative Pathology, Department of General Pathology, Biological Science Institute (ICB), Avenida Antônio Carlos 6627 Bloco C3 Sala 166
dc.description.affiliationVeterinary Hospital, Veterinary School, Department of Veterinary Clinic and Surgery
dc.description.affiliationUnespPostgraduate Program of Veterinary Medicine, School of Agricultural and Veterinary Sciences of the Sao Paulo State University (FCAV/UNESP), Jaboticabal Campus
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent863-866
dc.identifier.citationIn Vivo, v. 28, n. 5, p. 863-866, 2014.
dc.identifier.issn1791-7549
dc.identifier.issn0258-851X
dc.identifier.scopus2-s2.0-84918578265
dc.identifier.urihttp://hdl.handle.net/11449/167730
dc.language.isoeng
dc.relation.ispartofIn Vivo
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectCarboplatin
dc.subjectChemotherapy
dc.subjectFeline
dc.subjectMammary gland
dc.subjectNeoplasm
dc.titleUse of surgery and carboplatin in feline malignant mammary gland neoplasms with advanced clinical stagingen
dc.typeArtigo
dspace.entity.typePublication

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