Cell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemia
dc.contributor.author | Oliveira, Silvio Luis de [UNESP] | |
dc.contributor.author | Silva, Marcelo Fernandes da [UNESP] | |
dc.contributor.author | Soares, Angela Maria Victoriano de Campos [UNESP] | |
dc.contributor.author | Silva, Celio Lopes | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.date.accessioned | 2014-05-27T11:17:30Z | |
dc.date.available | 2014-05-27T11:17:30Z | |
dc.date.issued | 1993-01-01 | |
dc.description.abstract | The antibody response against the antigen sheep red blood cells (SRBC) was investigated in mice pre-treated with formalin-killed Paracoccidioides brasiliensis or with cell wall fractions of the fungus. Pre-treatment with P. brasiliensis, as well as with the F1 fraction and beta-glucan significantly increased the anti-SRBC antibody response in the experimental groups as compared to the control group that received only SRBC. This immunomodulatory effect varied with the different doses employed and with pre-treatment time. We conclude that the cell wall fractions of P. brasiliensis might play an important role in the hypergammaglobulinemia associated with Paracoccidioidomycosis. © 1993 Kluwer Academic Publishers. | en |
dc.description.affiliation | Department of Microbiology and Immunology UNESP, Botucatu, SP | |
dc.description.affiliation | Department of Parasitology, Microbiology and Immunology, School of Medicine of Ribeirao Preto University of Sao Paulo, Ribeirao Preto, SP, 14049 -900 | |
dc.description.affiliationUnesp | Department of Microbiology and Immunology UNESP, Botucatu, SP | |
dc.format.extent | 1-5 | |
dc.identifier | http://dx.doi.org/10.1007/BF01103346 | |
dc.identifier.citation | Mycopathologia, v. 121, n. 1, p. 1-5, 1993. | |
dc.identifier.doi | 10.1007/BF01103346 | |
dc.identifier.issn | 0301-486X | |
dc.identifier.issn | 1573-0832 | |
dc.identifier.lattes | 8418958338241095 | |
dc.identifier.scopus | 2-s2.0-0027349345 | |
dc.identifier.uri | http://hdl.handle.net/11449/64333 | |
dc.language.iso | eng | |
dc.relation.ispartof | Mycopathologia | |
dc.relation.ispartofjcr | 1.476 | |
dc.relation.ispartofsjr | 0,597 | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Scopus | |
dc.subject | Beta-glucan | |
dc.subject | Cell wall | |
dc.subject | Hypergammaglobulinemia | |
dc.subject | Paracoccidioides brasiliensis | |
dc.subject | Paracoccidioidomycosis | |
dc.title | Cell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemia | en |
dc.type | Artigo | |
dcterms.license | http://www.springer.com/open+access/authors+rights | |
unesp.author.lattes | 8418958338241095 | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatu | pt |