Risk factors for major complications after surgical treatment of primary ileocecal Crohn's disease. A multicenter Latin American experience

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dc.contributor.authorNicolás, Avellaneda
dc.contributor.authorRodrigues Coy, Claudio Saddy
dc.contributor.authorHenrique, Sarubbi Fillmann
dc.contributor.authorRogerio, Saad-Hossne [UNESP]
dc.contributor.authorPablo, Muñoz Juan
dc.contributor.authorRafael, García-Duperly
dc.contributor.authorFelipe, Bellolio
dc.contributor.authorNicolás, Rotholtz
dc.contributor.authorGustavo, Rossi
dc.contributor.authorRicardo, Marquez V Juan
dc.contributor.authorMariano, Cillo
dc.contributor.authorAntonio, Lacerda-Filho
dc.contributor.authorAugusto, Carrie
dc.contributor.authorBeatriz, Yuki Maruyama
dc.contributor.authorLucio, Sarubbi Fillmann
dc.contributor.authorMaria, Silvino Craveiro Marcela [UNESP]
dc.contributor.authorEzequiel, Ferro
dc.contributor.authorEduardo, Londoño-Schimmer
dc.contributor.authorAndrés, Iglesias
dc.contributor.authorCamila, Bras Harriott
dc.contributor.authorPablo, Campana Juan
dc.contributor.authorDaniel, Londoño Estrada
dc.contributor.authorRogini, Balachandran
dc.contributor.authorGustavo, Kotze Paulo
dc.contributor.institutionHospital Universitario CEMIC
dc.contributor.institutionAarhus University Hospital
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionPontificia Universidad Católica de Rio Grande do Sul
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionNueva Proctología
dc.contributor.institutionFundación Santa Fé de Bogotá
dc.contributor.institutionPontíficia Universidad Católica de Chile
dc.contributor.institutionHospital Aleman de Buenos Aires
dc.contributor.institutionHospital Italiano de Buenos Aires
dc.contributor.institutionClínica Las Américas
dc.contributor.institutionHospital Británico de Buenos Aires
dc.contributor.institutionFelicio Rocho Hospital
dc.contributor.institutionPontificia Universidade Católica do Paraná (PUCPR)
dc.date.accessioned2023-07-29T13:19:17Z
dc.date.available2023-07-29T13:19:17Z
dc.date.issued2023-01-01
dc.description.abstractIntroduction: Complications after ileocecal resection for Crohn's disease (CD) are frequent. The aim of this study was to analyze risk factors for postoperative complications after these procedures. Materials and methods: We conducted a retrospective analysis of patients treated surgically for Crohn's disease limited to the ileocecal region during an 8-year period at 10 medical centers specialized in inflammatory bowel disease (IBD) in Latin America. Patients were allocated into 2 groups: those who presented major postoperative complications (Clavien-Dindo > II), the “postoperative complication” (POC) group; and those who did not, the “no postoperative complication” (NPOC) group. Preoperative characteristics and intraoperative variables were analyzed to identify possible factors for POC. Results: In total, 337 patients were included, with 51 (15.13%) in the POC cohort. Smoking was more prevalent among the POC patients (31.37 vs 17.83; p = 0.026), who presented more preoperative anemia (33.33 vs 17.48%; p = 0.009), required more urgent care (37.25 vs 22.38; p = 0.023), and had lower albumin levels. Complicated disease was associated with higher postoperative morbidity. POC patients had a longer operative time (188.77 vs 143.86 min; p = 0.005), more intraoperative complications (17.65 vs 4.55%; p < 0.001), and lower rates of primary anastomosis. In the multivariate analysis, both smoking and intraoperative complications were independently associated with the occurrence of major postoperative complications. Conclusion: This study shows that risk factors for complications after primary ileocecal resections for Crohn's disease in Latin America are similar to those reported elsewhere. Future efforts in the region should be aimed at improving these outcomes by controlling some of the identified factors.en
dc.description.affiliationGeneral Surgery Department Hospital Universitario CEMIC
dc.description.affiliationColorectal Surgery Department Aarhus University Hospital
dc.description.affiliationColorectal Surgery Unit Campinas State University (UNICAMP)
dc.description.affiliationSurgery Department Pontificia Universidad Católica de Rio Grande do Sul
dc.description.affiliationColorectal Surgery Department Paulista State University UNESP
dc.description.affiliationColorectal Surgery Department Nueva Proctología
dc.description.affiliationColorectal Surgery Department Fundación Santa Fé de Bogotá
dc.description.affiliationColoproctology Unit Digestive Surgery Department Pontíficia Universidad Católica de Chile
dc.description.affiliationColorectal Surgery Service General Surgery Department Hospital Aleman de Buenos Aires
dc.description.affiliationSection of Colorectal Surgery Department of General Surgery Hospital Italiano de Buenos Aires
dc.description.affiliationColoproctology Institute Clínica Las Américas
dc.description.affiliationColorectal Surgery Department Hospital Británico de Buenos Aires
dc.description.affiliationDepartment of Colorectal Surgery Felicio Rocho Hospital
dc.description.affiliationColorectal Surgery Unit Pontificia Universidade Católica do Paraná (PUCPR)
dc.description.affiliationUnespColorectal Surgery Department Paulista State University UNESP
dc.identifierhttp://dx.doi.org/10.1016/j.ciresp.2023.04.001
dc.identifier.citationCirugia Espanola.
dc.identifier.doi10.1016/j.ciresp.2023.04.001
dc.identifier.issn1578-147X
dc.identifier.issn0009-739X
dc.identifier.scopus2-s2.0-85161477956
dc.identifier.urihttp://hdl.handle.net/11449/247555
dc.language.isoeng
dc.language.isospa
dc.relation.ispartofCirugia Espanola
dc.sourceScopus
dc.subjectComplication
dc.subjectCrohn
dc.subjectIBD
dc.subjectIleocecal
dc.subjectResection
dc.subjectRisk
dc.titleRisk factors for major complications after surgical treatment of primary ileocecal Crohn's disease. A multicenter Latin American experienceen
dc.titleFactores de riesgo para complicaciones mayores posteriores al tratamiento quirúrgico de la enfermedad de Crohn con afectación ileocecal. Trabajo retrospectivo, multicéntrico en América Latinaes
dc.typeArtigo

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