Effect of peritoneal dialysis vs. haemodialysis on respiratory mechanics in acute kidney injury patients

dc.contributor.authorAlmeida, Cibele Puato [UNESP]
dc.contributor.authorBalbi, André Luís [UNESP]
dc.contributor.authorPonce, Daniela [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:20:47Z
dc.date.available2018-12-11T17:20:47Z
dc.date.issued2018-06-11
dc.description.abstractBackground: Peritoneal dialysis (PD) and hemodialysis (HD) are options for the treatment of acute kidney injury (AKI) patients. The aim of this study was to compare the effects of PD and daily HD on respiratory mechanics of AKI patients undergoing invasive mechanical ventilation (IMV). Methods: A prospective cohort study evaluated 154 patients, 37 on continuous PD and 94 on HD. Respiratory mechanics parameters such as pulmonary static compliance (Psc) and resistance of the respiratory system (Rsr) and oxygenation index (OI) were assessed for 3 days. Patients were evaluated at moments 1, 2 and 3 (pre- and post-dialysis). Results: The initial clinical parameters were similar in the two groups, except the age that was higher in continuous PD group (70.8 ± 11.6 vs. 60 ± 15.8; p < 0.0001). In both groups, Psc increased significantly, with no difference between the two groups—pre-dialysis (continuous PD 40 ± 17.4, 42.8 ± 17.2, 48 ± 19; HD 39.1 ± 21.3, 39. 5 ± 18.9, 45.2 ± 21) and post-dialysis (continuous PD 42.8 ± 7.2, 48 ± 19, 57.1 ± 18.3; HD 42 ± 19, 45 ± 18.5, 56 ± 24.8). Rsr remained stable among patients on continuous PD (pre-dialysis 10.4 ± 5.1, 13.3 ± 7.7, 13.5 ± 10.3, post-dialysis 13.3 ± 7.7, 13.5 ± 10.3, 11.1 ± 5.9) and decreased among HD patients (pre-dialysis 10.4 ± 5.1, 10.4 ± 5.1, 10.4 ± 5, 1, post-dialysis 10.5 ± 6.8, 10 ± 4.9, 8.9 ± 4.2). There was difference in Rsr between the two groups at the post-dialysis moments 1 and 2 (p = 0.03). OI increased in both groups (continuous PD 260.7 ± 119, 252.7 ± 87.1, 287.3 ± 88.4; HD 228 ± 85, 257 ± 84, 312.1 ± 111.5, p > 0.05), although there was no difference between them. Conclusion: AKI patients undergoing IMV and HD or PD had improvement in the mechanical ventilation and oxygenation, with no difference between the two groups.en
dc.description.affiliationDepartment of Internal Medicine Botucatu Medical School UNESP Univ Estadual Paulista
dc.description.affiliationUnespDepartment of Internal Medicine Botucatu Medical School UNESP Univ Estadual Paulista
dc.format.extent1-7
dc.identifierhttp://dx.doi.org/10.1007/s10157-018-1598-7
dc.identifier.citationClinical and Experimental Nephrology, p. 1-7.
dc.identifier.doi10.1007/s10157-018-1598-7
dc.identifier.file2-s2.0-85048365129.pdf
dc.identifier.issn1437-7799
dc.identifier.issn1342-1751
dc.identifier.scopus2-s2.0-85048365129
dc.identifier.urihttp://hdl.handle.net/11449/176434
dc.language.isoeng
dc.relation.ispartofClinical and Experimental Nephrology
dc.relation.ispartofsjr0,711
dc.relation.ispartofsjr0,711
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAcute kidney injury
dc.subjectContinuous peritoneal dialysis
dc.subjectDaily hemodialysis
dc.subjectOxygenation and invasive mechanical ventilation
dc.subjectRespiratory mechanics
dc.titleEffect of peritoneal dialysis vs. haemodialysis on respiratory mechanics in acute kidney injury patientsen
dc.typeArtigo
unesp.author.lattes5697804493071661[2]
unesp.author.orcid0000-0001-8366-5064[2]
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