Influence of dental fillings and tooth type on the performance of a novel artificial intelligence-driven tool for automatic tooth segmentation on CBCT images – A validation study

dc.contributor.authorFontenele, Rocharles Cavalcante
dc.contributor.authorGerhardt, Maurício do Nascimento
dc.contributor.authorPinto, Jáder Camilo [UNESP]
dc.contributor.authorVan Gerven, Adriaan
dc.contributor.authorWillems, Holger
dc.contributor.authorJacobs, Reinhilde
dc.contributor.authorFreitas, Deborah Queiroz
dc.contributor.institutionFaculty of Medicine
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionPontifical Catholic University of Rio Grande do Sul
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionInnovatie-en incubatiecentrum KU Leuven
dc.contributor.institutionUniversity Hospitals Leuven
dc.contributor.institutionKarolinska Institute
dc.date.accessioned2022-04-28T19:51:46Z
dc.date.available2022-04-28T19:51:46Z
dc.date.issued2022-04-01
dc.description.abstractObjectives: To assess the influence of dental fillings on the performance of an artificial intelligence (AI)-driven tool for tooth segmentation on cone-beam computed tomography (CBCT) according to the type of tooth. Methods: A total of 175 CBCT scans (500 teeth) were recruited for performing training (140 CBCT scans - 400 teeth) and validation (35 CBCT scans - 100 teeth) of the AI convolutional neural networks. The test dataset involved 74 CBCT scans (226 teeth), which was further divided into control and experimental groups depending on the presence of dental filling: without filling (control group: 24 CBCT scans – 113 teeth) and with coronal and/or root filling (experimental group: 50 CBCT scans – 113 teeth). The segmentation performance for both groups was assessed. Additionally, 10% of each tooth type (anterior, premolar, and molar) was randomly selected for time analysis according to manual, AI-based and refined-AI segmentation methods. Results: The presence of fillings significantly influenced the segmentation performance (p<0.05). However, the accuracy metrics showed an excellent range of values for both control (95% Hausdorff Distance (95% HD): 0.01–0.08 mm; Intersection over union (IoU): 0.97–0.99; Dice similarity coefficient (DSC): 0.98–0.99; Precision: 1.00; Recall: 0.97–0.99; Accuracy: 1.00) and experimental groups (95% HD: 0.17–0.25 mm; IoU: 0.91–0.95; DSC: 0.95–0.97; Precision:1.00; Recall: 0.91–0.95; Accuracy: 0.99–1.00). The time analysis showed that the AI-based segmentation was significantly faster with a mean time of 29.8 s (p<0.001). Conclusions: The proposed AI-driven tool allowed an accurate and time-efficient approach for the segmentation of teeth on CBCT images irrespective of the presence of high-density dental filling material and the type of tooth. Clinical significance: Tooth segmentation is a challenging and time-consuming task, mainly in the presence of artifacts generated by dental filling material. The proposed AI-driven tool could offer a clinically acceptable approach for tooth segmentation, to be applied in the digital dental workflows considering its time efficiency and high accuracy regardless of the presence of dental fillings.en
dc.description.affiliationOMFS IMPATH Research Group Department of Imaging and Pathology Faculty of Medicine, KU Leuven
dc.description.affiliationDepartment of Oral Diagnosis University of Campinas
dc.description.affiliationDepartment of Prosthodontics Pontifical Catholic University of Rio Grande do Sul
dc.description.affiliationDepartment of Restorative Dentistry School of Dentistry UNESP - Universidade Estadual Paulista, SP
dc.description.affiliationRelu Innovatie-en incubatiecentrum KU Leuven
dc.description.affiliationDepartment of Oral and Maxillofacial Surgery University Hospitals Leuven
dc.description.affiliationDepartment of Dental Medicine Karolinska Institute, Stockholm
dc.description.affiliationUnespDepartment of Restorative Dentistry School of Dentistry UNESP - Universidade Estadual Paulista, SP
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdCAPES: 001
dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2022.104069
dc.identifier.citationJournal of Dentistry, v. 119.
dc.identifier.doi10.1016/j.jdent.2022.104069
dc.identifier.issn0300-5712
dc.identifier.scopus2-s2.0-85126095431
dc.identifier.urihttp://hdl.handle.net/11449/223607
dc.language.isoeng
dc.relation.ispartofJournal of Dentistry
dc.sourceScopus
dc.subjectArtificial intelligence
dc.subjectCone-beam computed tomography
dc.subjectConvolutional neural network
dc.subjectFillings
dc.subjectTooth
dc.titleInfluence of dental fillings and tooth type on the performance of a novel artificial intelligence-driven tool for automatic tooth segmentation on CBCT images – A validation studyen
dc.typeArtigo
unesp.author.orcid0000-0002-6426-9768 0000-0002-6426-9768[1]
unesp.author.orcid0000-0003-2757-9123 0000-0003-2757-9123[2]
unesp.author.orcid0000-0002-7843-0022[5]
unesp.author.orcid0000-0002-1425-5966[7]

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