Serodiagnosis

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dc.contributor.authorMendes-Giannini, Maria José S. [UNESP]
dc.contributor.authorDel Negro, Gilda Bárbaro
dc.contributor.authorSiqueira, Antonio Martins de
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionSchool of Pharmacy and Dentistry
dc.date.accessioned2019-10-06T17:06:16Z
dc.date.available2019-10-06T17:06:16Z
dc.date.issued2018-01-01
dc.description.abstractSerological methods are of considerable value in paracoccidioidomycosis. Counter-immunoelectrophoresis, otherwise known as electrosyneresis or immunoelectroosmophoresis, has been frequently applied for the immunodiagnosis of several mycotic disorders. The development of a standard serological test for paracoccidioidomycosis is therefore being intensively pursued and recently a study group has been set up for this purpose, under the auspices of the International Society for Human and Animal Mycology (ISHAM) and with the involvement of various laboratories. When evaluating the serological response of paracoccidioidomycosis patients to antigens present in P. brasiliensis yeast cells filtrate, in the ELISA and the erythro-immunoassay, it was found that absorption of the sera with dead Candida albicans cells was a requirement. The immunofluorescence test has also been used in the serodiagnosis of paracoccidioidomycosis as well as in the study of the antigenic relationship between pathogenic fungi. Improvement in the serodiagnosis of paracoccidioidomycosis will come from the use of purified immunodominant fractions as antigens.en
dc.description.affiliationDepartment of Clinical Pathology School of Pharmaceutical Sciences University of the State of São Paulo (UNESP)
dc.description.affiliationLaboratory of Medical Mycology São Paulo University Hospital (USP)
dc.description.affiliationDepartment of Biological Sciences School of Pharmacy and Dentistry
dc.description.affiliationUnespDepartment of Clinical Pathology School of Pharmaceutical Sciences University of the State of São Paulo (UNESP)
dc.format.extent345-363
dc.identifierhttp://dx.doi.org/10.1201/9781351075329
dc.identifier.citationParacoccidioidomycosis, p. 345-363.
dc.identifier.doi10.1201/9781351075329
dc.identifier.scopus2-s2.0-85063463621
dc.identifier.urihttp://hdl.handle.net/11449/190223
dc.language.isoeng
dc.relation.ispartofParacoccidioidomycosis
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.titleSerodiagnosisen
dc.typeCapítulo de livro
unesp.departmentAnálises Clínicas - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas