Evaluation of antimicrobial photodynamic therapy against Streptococcus mutans biofilm in situ

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Panhóca, V. H.
Florez, F. L.E. [UNESP]
de Faria, N. Batista [UNESP]
Rastelli, Alessandra Nara de Souza [UNESP]
Tanomaru, J. M.G. [UNESP]
Kurachi, C.
Bagnato, V. S.
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Aim: This study investigated the effect of antimicrobial photodynamic therapy (aPDT) over Streptococcus mutans biofilm. Materials and methods: Eighteen (n = 18) patients were selected and one palatine device with dental blocks was used. The biofilm was treated by curcumin and Photogem® with a LED and the effect was analyzed by CFU/ml. Results: Although, statistical analysis showed significant reductions for aPDT mainly with Photogem® (p = 0.02), these were low. Conclusion: The results suggest a low antimicrobial effect of aPDT over S. mutans biofilm. Some parameters used need to be improved. Clinical Significance: This technique can be a promising in Dentistry.
Biofilm, Curcumin, Dental caries, Photodynamic therapy, Randomized clinical trial, Streptococcus mutans
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Journal of Contemporary Dental Practice, v. 17, n. 3, p. 184-191, 2016.