Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool

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dc.contributor.authorReis, Leonardo Oliveira
dc.contributor.authorSopena, Josep Maria Gaya
dc.contributor.authorFávaro, Wagner José [UNESP]
dc.contributor.authorMartin, Mireia Castilho
dc.contributor.authorSimão, Antônio Felipe Leite
dc.contributor.authorReis, Rodolfo Borges dos
dc.contributor.authorAndrade, Murilo Ferreira de
dc.contributor.authorDomenech, Josep Domingo
dc.contributor.authorCardo, Carlos Cordon
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionColumbia University
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:26:07Z
dc.date.available2014-05-27T11:26:07Z
dc.date.issued2011-11-10
dc.description.abstractPURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.en
dc.description.affiliationUrologic Oncology Division Department of Urology University of Campinas (UNICAMP), Campinas-SP
dc.description.affiliationHerbert Irving Comprehensive Cancer Center Columbia University, New York, NY
dc.description.affiliationDepartment of Anatomy, Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-SP
dc.description.affiliationDivision of Urology Department of Surgery and Anatomy, Ribeirao Preto-SP
dc.description.affiliationUrologic Division Department of Surgery and Anatomy, FMRP-USP, Ribeirao Preto-SP
dc.description.affiliationHerbert Irving Comprehensive Cancer Center Columbia University, New York, New York
dc.description.affiliationUnespDepartment of Anatomy, Institute of Biosciences Universidade Estadual Paulista (UNESP), Botucatu-SP
dc.format.extent106-110
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502011000800019
dc.identifier.citationActa Cirurgica Brasileira, v. 26, n. SUPPL. 2, p. 106-110, 2011.
dc.identifier.doi10.1590/S0102-86502011000800019
dc.identifier.file2-s2.0-80555124917.pdf
dc.identifier.issn0102-8650
dc.identifier.issn1678-2674
dc.identifier.scieloS0102-86502011000800019
dc.identifier.scopus2-s2.0-80555124917
dc.identifier.urihttp://hdl.handle.net/11449/72792
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofActa Cirúrgica Brasileira
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAnatomy
dc.subjectRats
dc.subjectRodent diseases
dc.subjectUrinary tract
dc.subjectanimal anatomy
dc.subjectanimal experiment
dc.subjectbladder
dc.subjectbladder catheterization
dc.subjectcancer research
dc.subjectcarcinogenesis
dc.subjectcost benefit analysis
dc.subjectfemale
dc.subjectmouse
dc.subjectnonhuman
dc.subjectrat
dc.subjecttoxicity testing
dc.subjecturethra
dc.subjecturethral catheterization
dc.subjectvesicoureteral reflux
dc.subjectAnimals
dc.subjectFemale
dc.subjectMedical Illustration
dc.subjectMice
dc.subjectModels, Animal
dc.subjectReproducibility of Results
dc.subjectSex Factors
dc.subjectUrethra
dc.subjectUrinary Bladder
dc.subjectUrinary Catheterization
dc.titleAnatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational toolen
dc.title.alternativeCaracterísticas anatômicas da cateterização da uretra e bexiga de camundongos e ratos fêmeas. instrumento essencial na pesquisa pré clínicapt
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/acb/iaboutj.htm
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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Artigos - Anatomia - IBB