Morphological changes on the hard palatine mucosa of rats (Rattus norvegicus albinus) after chronic alcohol consumption

dc.contributor.authorMartinez, M.
dc.contributor.authorMartinez, F. E.
dc.contributor.authorWatanabe, I.
dc.contributor.institutionFed. University of São Carlos
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2022-04-29T08:42:41Z
dc.date.available2022-04-29T08:42:41Z
dc.date.issued1998-07-01
dc.description.abstractIn order to examine the effects of alcohol on the hard palatine mucosa of rats, sixty adult female rats (Rattus norvegicus albinus) were divided into two experimental groups. The control group received solid diet (Purina rat chow) and tap water ad libitum. The alcoholic group received the same solid diet and was allowed to drink only sugar cane brandy dissolved in 30% Gay Lussac (v/v). At the end of periods of 90, 180 and 270 days of treatment, the animals at estro were sacrificed and the hard palatine mucosa were prepared for TEM and SEM methods. The basal cells of the alcoholic groups (90, 180 and 270 days of treatment) demonstrated some alterations: the intercellular spaces between these cells were higher, presented cytoplasmatic lipid droplets and autolysis. Also, the connective tissue showed intense lipid droplets accumulation in the alcoholic groups. These modifications suggested that chronic alcohol ingestion was able to modify the integrity of the cells in the rat hard palatine mucosa.en
dc.description.affiliationDepartment of Anatomy and Pathology Fed. University of São Carlos, São Carlos, SP
dc.description.affiliationDepartment of Anatomy Institute of Biosciences State University of São Paulo, Botucatu, SP
dc.description.affiliationDepartment of Anatomy Institute of Biomedical Sciences University of São Paulo (USP), São Paulo, SP
dc.description.affiliationDepartamento de Anatomia e Patologia Univ. Federal de São Carlos, Via Washington Luis Km. 235, CEP 13565-905 São Carlos, SP
dc.format.extent379-384
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology, v. 30, n. 3, p. 379-384, 1998.
dc.identifier.issn1122-9497
dc.identifier.scopus2-s2.0-0032110211
dc.identifier.urihttp://hdl.handle.net/11449/230901
dc.language.isoeng
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.sourceScopus
dc.subjectAlcohol
dc.subjectConnective tissue
dc.subjectEpithelium
dc.subjectPaldtine mucosa
dc.titleMorphological changes on the hard palatine mucosa of rats (Rattus norvegicus albinus) after chronic alcohol consumptionen
dc.typeArtigo

Arquivos