Subcutaneous tissue reaction to modified Portland cement (CPM)

dc.contributor.authorGomes Filho, João Eduardo [UNESP]
dc.contributor.authorFaria, Max Douglas [UNESP]
dc.contributor.authorWatanabe, Simone [UNESP]
dc.contributor.authorLodi, Carolina Simonetti [UNESP]
dc.contributor.authorCintra, Luciano Tavares Angelo [UNESP]
dc.contributor.authorDezan Junior, Eloi [UNESP]
dc.contributor.authorBernabé, Pedro Felício Estrada [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T15:27:03Z
dc.date.available2022-04-29T15:27:03Z
dc.date.issued2012-01-01
dc.description.abstractIntroduction: The aim of this study was to evaluate the rat subcutaneous tissue response to implanted polyethylene tubes filled with Modified Portland Cement (CPM®) (Egeo S.R.L., Buenos Aires, Argentina) compared with Angelus MTA® (Angelus, Londrina, Brazil). Methods: These materials were placed in polyethylene tubes and implanted into dorsal connective tissue of Wistar rats for 7, 15, 30, 60, and 90 days. The specimens were prepared and stained with hematoxylin and eosin or Von Kossa or not stained for polarized light. Qualitative and quantitative evaluations of the reaction were performed. Results: Both materials caused moderate reactions at 7 days that decreased with time. Angelus MTA® caused mild reactions at 15 days that decreased with time. The response was similar to the control on 30, 60 and 90 days with CPM® and Angelus MTA®. Mineralization and birefringent to the polarized light granulations were observed with both materials. Conclusions: It was possible to conclude that CPM® and Angelus MTA® were biocompatible in the rat model, and that they stimulated mineralization.en
dc.description.affiliationFOA-UNESP
dc.description.affiliationUnespFOA-UNESP
dc.format.extent47-52
dc.identifier.citationDental Press Endodontics, v. 2, n. 2, p. 47-52, 2012.
dc.identifier.issn2178-3713
dc.identifier.scopus2-s2.0-84930920133
dc.identifier.urihttp://hdl.handle.net/11449/232413
dc.language.isoeng
dc.relation.ispartofDental Press Endodontics
dc.sourceScopus
dc.subjectBiocompatibility
dc.subjectConnective tissue
dc.subjectMineral trioxide aggregate
dc.titleSubcutaneous tissue reaction to modified Portland cement (CPM)en
dc.typeArtigo

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