Salvage robot assisted radical prostatectomy: A propensity matched study of perioperative, oncological and functional outcomes

dc.contributor.authorBates, A. S.
dc.contributor.authorSamavedi, S.
dc.contributor.authorKumar, A.
dc.contributor.authorMouraviev, V.
dc.contributor.authorRocco, B.
dc.contributor.authorCoelho, R.
dc.contributor.authorPalmer, K.
dc.contributor.authorPatel, V. R.
dc.contributor.institutionUniversity of Central Florida College of Medicine
dc.contributor.institutionUniversity of Milan
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2022-04-28T19:01:38Z
dc.date.available2022-04-28T19:01:38Z
dc.date.issued2015-11-01
dc.description.abstractBackground To report the perioperative, functional and oncological outcomes of salvage robot-assisted laparoscopic prostatectomy (s-RARP) in a propensity score-matched analysis. Study design 53 patients underwent s-RARP at our institution. Perioperative, functional and oncological outcomes were compared between propensity matched cohorts. Results Patients in the s-RARP group were at significantly higher risk based on the D'Amico classification system (p = 0.010). Estimated blood loss, complication rate, hospital stay, BCR risk, persistent cancer and time to return of potency were similar between groups (full nerve spare [NS] n = 22). In the s-RARP cohort there was a higher prevalence of lymphovascular invasion (26.4% versus 13.2%; p = 0.032), time to catheter removal and a higher prevalence of anastomotic leaks in the postoperative period (34.0% vs 5.7%, p < 0.010). The hazard ratio for return to potency regardless of nerve sparing in the s-RARP group was 0.47 (95% CI 0.25-0.88). Significantly more patients undergoing primary RARP with partial nerve sparing (NS) recovered continence (p < 0.001) and potency (p = 0.043) compared to partial NS s-RARP patients. The return to continence and potency did not differ between full NS cases (n = 22; p = 0.616). Conclusions Salvage RARP patients undergoing surgery have more high risk disease. Patients should be counseled that they are more likely to demonstrate anastomotic leakage on cystogram, and prolonged catheterization times. The time to potency and continence in s-RARP undergoing partial and no NS was significantly delayed (n = 49). The proportion of patients returning to potency and continence was also lower in our s-RARP group.en
dc.description.affiliationGlobal Robotics Institute Florida Hospital-Celebration Health University of Central Florida College of Medicine
dc.description.affiliationDepartment of Urology Fondazione Ospedale Maggiore Policlinico University of Milan
dc.description.affiliationUniversity of Sao Paulo State Cancer Institute
dc.format.extent1540-1546
dc.identifierhttp://dx.doi.org/10.1016/j.ejso.2015.06.002
dc.identifier.citationEuropean Journal of Surgical Oncology, v. 41, n. 11, p. 1540-1546, 2015.
dc.identifier.doi10.1016/j.ejso.2015.06.002
dc.identifier.issn1532-2157
dc.identifier.issn0748-7983
dc.identifier.scopus2-s2.0-84943586853
dc.identifier.urihttp://hdl.handle.net/11449/220465
dc.language.isoeng
dc.relation.ispartofEuropean Journal of Surgical Oncology
dc.sourceScopus
dc.subjectOncological outcomes
dc.subjectPotency
dc.subjectRobotic assisted radical prostatectomy
dc.subjectSalvage prostatectomy
dc.subjectUrinary incontinence
dc.titleSalvage robot assisted radical prostatectomy: A propensity matched study of perioperative, oncological and functional outcomesen
dc.typeArtigo

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