Biocompatibility, bioactive potential, porosity, and interface analysis calcium silicate repair cements in a dentin tube model
dc.contributor.author | Inada, Rafaela Nanami Handa [UNESP] | |
dc.contributor.author | Queiroz, Marcela Borsatto [UNESP] | |
dc.contributor.author | Lopes, Camila Soares [UNESP] | |
dc.contributor.author | Silva, Evelin Carine Alves [UNESP] | |
dc.contributor.author | Torres, Fernanda Ferrari Esteves [UNESP] | |
dc.contributor.author | da Silva, Guilherme Ferreira | |
dc.contributor.author | Guerreiro-Tanomaru, Juliane Maria [UNESP] | |
dc.contributor.author | Cerri, Paulo Sérgio [UNESP] | |
dc.contributor.author | Tanomaru-Filho, Mário [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
dc.contributor.institution | Centro Universitário Sagrado Coração (UNISAGRADO) | |
dc.date.accessioned | 2023-07-29T16:10:07Z | |
dc.date.available | 2023-07-29T16:10:07Z | |
dc.date.issued | 2023-01-01 | |
dc.description.abstract | Objectives: This study is to evaluate biocompatibility, bioactive potential, porosity, and dentin/material interface of Bio-C Repair (BIOC-R), MTA Repair HP (MTAHP), and Intermediate Restorative Material (IRM). Materials and methods: Dentin tubes were implanted into subcutaneous of rats for 7, 15, 30, and 60 days. Thickness of capsules, number of inflammatory cells (ICs), interleukin-6 (IL-6), osteocalcin (OCN), and von Kossa were evaluated. Porosity and material/dentin interface voids were also analyzed. Data were submitted to ANOVA and Tukey’s tests (p < 0.05). Results: IRM capsules were thicker and contained greater ICs and IL-6-immunopositive cells at 7 and 15 days. BIOC-R capsules exhibited higher thickness and ICs at 7 days and greater IL-6 at 7 and 15 days than MTAHP (p < 0.05). At 30 and 60 days, no significant difference was observed among the groups. OCN-immunopositive cells, von Kossa-positive, and birefringent structures were observed in BIOC-R and MTAHP. MTAHP exhibited higher porosity and interface voids (p < 0.05). Conclusions: BIOC-R, MTAHP, and IRM are biocompatible. Bioceramics materials demonstrate bioactive potential. MTAHP presented the highest porosity and presence of voids. Clinical relevance: BIOC-R and MTAHP have adequate biological properties. BIOC-R demonstrated lower porosity and presence of voids, which may represent better sealing for its clinical applications. | en |
dc.description.affiliation | Department of Restorative Dentistry São Paulo State University (UNESP) School of Dentistry, Rua Humaitá, 1680, SP | |
dc.description.affiliation | Department of Dentistry Centro Universitário Sagrado Coração (UNISAGRADO), Rua Irmã Armida, 10-50, SP | |
dc.description.affiliation | Department of Morphology and Children Clinic São Paulo State University (UNESP) School of Dentistry, Rua Humaitá, 1680, SP | |
dc.description.affiliationUnesp | Department of Restorative Dentistry São Paulo State University (UNESP) School of Dentistry, Rua Humaitá, 1680, SP | |
dc.description.affiliationUnesp | Department of Morphology and Children Clinic São Paulo State University (UNESP) School of Dentistry, Rua Humaitá, 1680, SP | |
dc.identifier | http://dx.doi.org/10.1007/s00784-023-05002-5 | |
dc.identifier.citation | Clinical Oral Investigations. | |
dc.identifier.doi | 10.1007/s00784-023-05002-5 | |
dc.identifier.issn | 1436-3771 | |
dc.identifier.issn | 1432-6981 | |
dc.identifier.scopus | 2-s2.0-85151568697 | |
dc.identifier.uri | http://hdl.handle.net/11449/249820 | |
dc.language.iso | eng | |
dc.relation.ispartof | Clinical Oral Investigations | |
dc.source | Scopus | |
dc.subject | Biocompatibility | |
dc.subject | Calcium silicate | |
dc.subject | Root repair materials | |
dc.subject | X-ray microtomography | |
dc.title | Biocompatibility, bioactive potential, porosity, and interface analysis calcium silicate repair cements in a dentin tube model | en |
dc.type | Artigo | |
unesp.campus | Universidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquara | pt |
unesp.department | Morfologia - FOAR | pt |