Ampolas de Vidro: Riscos e Benefícios

dc.contributor.authorCarraretto, Antônio Roberto [UNESP]
dc.contributor.authorCuri, Erick Freitas
dc.contributor.authorde Almeida, Carlos Eduardo David
dc.contributor.authorAbatti, Roberta Eleni Monteiro
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Espírito Santo (UFES)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionCET Integrado HUCAM/HAFPES
dc.date.accessioned2014-05-27T11:25:55Z
dc.date.available2014-05-27T11:25:55Z
dc.date.issued2011-07-01
dc.description.abstractBackground and objectives: Glass ampoules have been widely used in packaging injection drugs. Glass has important characteristics that allow it to be widely used in fabrication of recipients for drugs and other sterile substances. However, contamination of solutions with glass microparticles on breaking open glass ampoules, the presence of metals, percutaneous injury, and biological contamination justify the need of educational materials to orient the manipulation of ampoules. Contents: Glass microparticles generated in the snap-opening of ampoules, as well as metals that contaminate their contents can be aspirated and injected through several routes. Exogenous contaminations by glass and metals can reach several sites in the organism. They trigger organic reactions that may give rise to injuries. Opening ampoules can expose professionals to the risk of percutaneous injuries. These lesions increase the biological risk as they are the gateway for viruses and bacteria. Ampoules opening systems (VIBRAC and OPC) have been developed to reduce the incidence of such accidents. Alternative materials to glass may represent an interesting strategy to increase safety. The use of prefilled syringes may represent an evolution regarding safety. Conclusions: Team training and information provided by the pharmaceutical industry on the use of ampoules are fundamental in the prophylaxis of accidents and contaminations. The search for safer materials to replace glass is also important. © 2011 Elsevier Editora Ltda.en
dc.description.affiliationUNESP
dc.description.affiliationSociedade de Anestesiologia do Espírito Santo - SAES CET Integrado HUCAM/HAFPES Physician of Serviço de Anestesiologia do HUCAM - UFES
dc.description.affiliationUniversidade de São Paulo (USP) Physician of Serviço de Anestesiologia do HUCAM - UFES
dc.description.affiliationCET Integrado HUCAM/HAFPES
dc.description.affiliationDepartamento de Clínica Cirúrgica da UFES CET Integrado HUCAM/HAFPES
dc.description.affiliationUnespUNESP
dc.format.extent513-521
dc.identifierhttp://dx.doi.org/10.1016/S0034-7094(11)70059-9
dc.identifier.citationRevista Brasileira de Anestesiologia, v. 61, n. 4, p. 513-521, 2011.
dc.identifier.doi10.1016/S0034-7094(11)70059-9
dc.identifier.file2-s2.0-80052516461.pdf
dc.identifier.issn0034-7094
dc.identifier.issn1806-907X
dc.identifier.scopus2-s2.0-80052516461
dc.identifier.urihttp://hdl.handle.net/11449/72511
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Anestesiologia
dc.relation.ispartofjcr0.850
dc.relation.ispartofsjr0,320
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAnesthesiology
dc.subjectDisposable equipment
dc.subjectEducation, medical, continuing
dc.subjectGlass
dc.subjectSafety management
dc.subjectglass
dc.subjectaccident
dc.subjectampoule
dc.subjectcontamination
dc.subjectdrug packaging
dc.subjectrisk
dc.subjectDrug Contamination
dc.subjectDrug Packaging
dc.subjectHealth Personnel
dc.subjectOccupational Injuries
dc.subjectRisk Factors
dc.subjectRisk Management
dc.titleAmpolas de Vidro: Riscos e Benefíciospt
dc.title.alternativeGlass Ampoules: Risks and Benefitsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy

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