Spontaneous resolution rates of vesicoureteral reflux in Brazilian children: A 30-year experience

dc.contributor.authorFilho, Miguel Zerati [UNESP]
dc.contributor.authorCalado, Adriano A. [UNESP]
dc.contributor.authorBarroso Jr., Ubirajara [UNESP]
dc.contributor.authorAmaro, João Luiz [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:25Z
dc.date.available2014-05-27T11:22:25Z
dc.date.issued2007-03-01
dc.description.abstractObjective: We evaluated clinical characteristics of primary vesicoureteral reflux (VLJR) in infants in a 30-year period in Brazil with special reference to the relation of renal parenchymal damage to urinary tract infection and gender. Materials and Methods: From 1975 through 2005, 417 girls (81.6%) and 94 boys (18.4%) with all grades of reflux were retrospectively reviewed. Patients were categorized by the worst grade of reflux, maintained on antibiotic prophylaxis and underwent yearly voiding cystourethrography until the reflux was resolved. VUR was considered resolved when a follow-up cystogram demonstrated no reflux. Surgical correction was recommended for those who fail medical therapy, severe renal scarring or persistent VUR. Results: Grades I to V VUR resolved in 87.5%, 77.6%, 52.8%, 12.2% and 4.3%, respectively. Renal scars were present at presentation in 98 patients (19.2%). Neither gender nor bilaterality versus unilaterality was a helpful predictor of resolution. The significant difference was found among the curves using the log rank (p < 0.001) or Wilcoxon (p < 0.001) test. Conclusion: Despite the current use of screening prenatal ultrasound, many infants are still diagnosed as having vesicoureteral reflux only after the occurrence of urinary tract infection in our country. Scarring may be associated to any reflux grade and it may be initially diagnosed at any age but half of the scars are noted with higher grades of reflux (IV and V). The incidence of reflux related morbidity in children has significantly diminished over the last three decades.en
dc.description.affiliationDivision of Urology Sao Paulo State University UNESP, Botucatu, Sao Paulo
dc.description.affiliation, Rua Conselheiro Portela 285/602, Recife, PE 52020-030
dc.description.affiliationUnespDivision of Urology Sao Paulo State University UNESP, Botucatu, Sao Paulo
dc.format.extent204-212
dc.identifierhttp://dx.doi.org/10.1590/S1677-55382007000200012
dc.identifier.citationInternational Braz J Urol, v. 33, n. 2, p. 204-212, 2007.
dc.identifier.doi10.1590/S1677-55382007000200012
dc.identifier.file2-s2.0-34249785121.pdf
dc.identifier.issn1677-5538
dc.identifier.issn1677-6119
dc.identifier.scieloS1677-55382007000200012
dc.identifier.scopus2-s2.0-34249785121
dc.identifier.urihttp://hdl.handle.net/11449/69560
dc.language.isoeng
dc.relation.ispartofInternational Braz J Urol
dc.relation.ispartofjcr0.976
dc.relation.ispartofsjr0,367
dc.relation.ispartofsjr0,367
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectReconstructive surgical procedures
dc.subjectUreter
dc.subjectVesico-ureteral reflux
dc.subjectantibiotic prophylaxis
dc.subjectchild
dc.subjectfemale
dc.subjectfollow up
dc.subjecthospitalization
dc.subjecthuman
dc.subjectinfant
dc.subjectkidney
dc.subjectmale
dc.subjectpathology
dc.subjectpathophysiology
dc.subjectpreschool child
dc.subjectremission
dc.subjectretrospective study
dc.subjectsex ratio
dc.subjecturinary tract infection
dc.subjecturography
dc.subjectvesicoureteral reflux
dc.subjectAntibiotic Prophylaxis
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectInfant
dc.subjectKidney
dc.subjectMale
dc.subjectRemission, Spontaneous
dc.subjectRetrospective Studies
dc.subjectSeverity of Illness Index
dc.subjectSex Distribution
dc.subjectUrinary Tract Infections
dc.subjectUrography
dc.subjectVesico-Ureteral Reflux
dc.titleSpontaneous resolution rates of vesicoureteral reflux in Brazilian children: A 30-year experienceen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/ibju/paboutj.htm
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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