Sample preparation combined with electroanalysis to improve simultaneous determination of antibiotics in animal derived food samples

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dc.contributor.authorda Silva, Wesley Pereira
dc.contributor.authorde Oliveira, Luiz Henrique
dc.contributor.authorSantos, André Luiz dos
dc.contributor.authorFerreira, Valdir Souza
dc.contributor.authorTrindade, Magno Aparecido Gonçalves [UNESP]
dc.contributor.institutionFaculty of Science and TechnologyFederal University of Grande Dourados
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade Federal de Mato Grosso do Sul (UFMS)
dc.date.accessioned2018-12-11T17:23:44Z
dc.date.available2018-12-11T17:23:44Z
dc.date.issued2018-06-01
dc.description.abstractA procedure based on liquid–liquid extraction (LLE) and phase separation using magnetically stirred salt-induced high-temperature liquid-liquid extraction (PS-MSSI-HT-LLE) was developed to extract and pre-concentrate ciprofloxacin (CIPRO) and enrofloxacin (ENRO) from animal food samples before electroanalysis. Firstly, simple LLE was used to extract the fluoroquinolones (FQs) from animal food samples, in which dilution was performed to reduce interference effects to below a tolerable threshold. Then, adapted PS-MSSI-HT-LLE protocols allowed re-extraction and further pre-concentration of target analytes in the diluted acid samples for simultaneous electrochemical quantification at low concentration levels. To improve the peak separation, in simultaneous detection, a baseline-corrected second-order derivative approach was processed. These approaches allowed quantification of target FQs from animal food samples spiked at levels of 0.80 to 2.00 µmol L−1 in chicken meat, with recovery values always higher than 80.5%, as well as in milk samples spiked at 4.00 µmol L−1, with recovery values close to 70.0%.en
dc.description.affiliationFaculty of Science and TechnologyFederal University of Grande Dourados, Rodovia Dourados- Itahum, km 12
dc.description.affiliationUnesp National Institute for Alternative Technologies of DetectionToxicological Evaluation and Removal of Micropollutants and Radioactives (INCT-DATREM) Institute of Chemistry, P.O. Box 355
dc.description.affiliationFaculdade de Ciências Integradas do PontalUniversidade Federal de Uberlândia, Rua 20, 1600 Bairro Tupã
dc.description.affiliationInstitute of ChemistryUniversidade Federal de Mato Grosso do Sul, Av. Filinto Muller, 1555, Caixa Postal 549, Campo Grande
dc.description.affiliationUnespUnesp National Institute for Alternative Technologies of DetectionToxicological Evaluation and Removal of Micropollutants and Radioactives (INCT-DATREM) Institute of Chemistry, P.O. Box 355
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdCNPq: 402832/2016-7
dc.description.sponsorshipIdCAPES: 88881.119436/2016-01
dc.format.extent7-13
dc.identifierhttp://dx.doi.org/10.1016/j.foodchem.2018.01.041
dc.identifier.citationFood Chemistry, v. 250, p. 7-13.
dc.identifier.doi10.1016/j.foodchem.2018.01.041
dc.identifier.issn1873-7072
dc.identifier.issn0308-8146
dc.identifier.scopus2-s2.0-85039986903
dc.identifier.urihttp://hdl.handle.net/11449/177075
dc.language.isoeng
dc.relation.ispartofFood Chemistry
dc.relation.ispartofsjr1,793
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBiological sample preparation
dc.subjectComplex feedstuff samples
dc.subjectElectroanalysis
dc.subjectResidual veterinary drugs
dc.titleSample preparation combined with electroanalysis to improve simultaneous determination of antibiotics in animal derived food samplesen
dc.typeArtigo

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