Monitoring and Treatment of Juvenile Idiopathic Arthritis-associated Uveitis: Brazilian Evidence-based Practice Guidelines

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dc.contributor.authorNeves, L. M.
dc.contributor.authorHaefeli, L. M.
dc.contributor.authorHopker, L. M.
dc.contributor.authorEjzenbaum, F.
dc.contributor.authorMoraes do Nascimento, H.
dc.contributor.authorAikawa, N.
dc.contributor.authorHilario, M. O.
dc.contributor.authorMagalhães, C. S. [UNESP]
dc.contributor.authorTerreri, M. T.
dc.contributor.authorSztajnbok, F.
dc.contributor.authorSilva, C. A.A.
dc.contributor.authorRossetto, J. D.
dc.contributor.institutionDa Criança E Do Adolescente Fernandes Figueira- Fundação Oswaldo Cruz
dc.contributor.institutionBrazilian Society of Pediatric Ophthalmology (SBOP)
dc.contributor.institutionBrazilian Council of Ophthalmology (CBO)
dc.contributor.institutionOphthalmology Department
dc.contributor.institutionBrazilian Society of Pediatrics (SBP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionBrazilian Society of Rheumatology (SBR)
dc.contributor.institutionSanta Casa De Misericórdia De Porto Alegre
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.date.accessioned2021-06-25T11:03:25Z
dc.date.available2021-06-25T11:03:25Z
dc.date.issued2021-01-01
dc.description.abstractPurpose: To present a national guideline for ophthalmologic care and surveillance of juvenile idiopathic arthritis-associated uveitis (JIA-uveitis).Methods: Review article based on medical literature and the experience of an Expert Committee composed of members of the Brazilian Society of Pediatric Ophthalmology/Brazilian Council of Ophthalmology and the Brazilian Society of Pediatrics/Brazilian Society of Rheumatology. Studies with a high level of evidence were selected by searching the PubMed/Medline database. The final document was approved by the experts.Results: The main recommendations are that children/adolescents with JIA should undergo screening according to their risk factors. Ophthalmological checkups should also consider ocular inflammation and therapy. Topical glucocorticoids should be the first line of therapy, with systemic glucocorticoids acting as bridge treatments in severe uveitis. Methotrexate should be the first-line systemic therapy and anti-tumor necrosis factor (anti-TNF alpha) the second for uncontrolled uveitis.Conclusions: This evidence-based guideline for JIA-uveitis will be useful for both ophthalmology and rheumatology practice.en
dc.description.affiliationOphthalmology Department Instituto Nacional De Saúde Da Mulher Da Criança E Do Adolescente Fernandes Figueira- Fundação Oswaldo Cruz
dc.description.affiliationBrazilian Society of Pediatric Ophthalmology (SBOP)
dc.description.affiliationBrazilian Council of Ophthalmology (CBO)
dc.description.affiliationOphthalmology Department, Hospital De Olhos Do Paraná
dc.description.affiliationBrazilian Society of Pediatrics (SBP)
dc.description.affiliationOphthalmology Department, Santa Casa De Misericórdia De
dc.description.affiliationOphthalmology and Visual Science Department Federal University of Sao Paulo – UNIFESP
dc.description.affiliationPediatric Rheumatology Unit Children’s Institute Hospital Das Clinicas HCFMUSP Faculdade De Medicina Universidade De Sao Paulo
dc.description.affiliationBrazilian Society of Rheumatology (SBR)
dc.description.affiliationPediatric Department Santa Casa De Misericórdia De Porto Alegre
dc.description.affiliationPediatric Rheumatology Division São Paulo State University (UNESP)
dc.description.affiliationPediatric Rheumatology Unit Federal University of São Paulo – UNIFESP
dc.description.affiliationPediatric Department Instituto De Puericultura E Pediatria Martagão Gesteira - IPPMG/Federal University of Rio De Janeiro - UFRJ
dc.description.affiliationUnespPediatric Rheumatology Division São Paulo State University (UNESP)
dc.identifierhttp://dx.doi.org/10.1080/09273948.2021.1876886
dc.identifier.citationOcular Immunology and Inflammation.
dc.identifier.doi10.1080/09273948.2021.1876886
dc.identifier.issn1744-5078
dc.identifier.issn0927-3948
dc.identifier.lattes7098310008371632
dc.identifier.orcid0000-0002-7631-7093
dc.identifier.scopus2-s2.0-85103877501
dc.identifier.urihttp://hdl.handle.net/11449/207928
dc.language.isoeng
dc.relation.ispartofOcular Immunology and Inflammation
dc.sourceScopus
dc.subjectanterior uveitis
dc.subjectchildhood
dc.subjectJuvenile idiopathic arthritis
dc.subjectmethotrexate
dc.subjectpractice guideline
dc.subjecttumor necrosis factor-alpha
dc.titleMonitoring and Treatment of Juvenile Idiopathic Arthritis-associated Uveitis: Brazilian Evidence-based Practice Guidelinesen
dc.typeArtigo
unesp.author.lattes7098310008371632[8]
unesp.author.orcid0000-0003-0315-1317[5]
unesp.author.orcid0000-0002-7631-7093[8]

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