Comparative ''in vitro'' study on the susceptibility and emergence of mutants resistant to danofloxacin and ciprofloxacin among Staphylococcus aureus isolated from bovine mastitis

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dc.contributor.authorCruz, A. D.
dc.contributor.authorLopes, CADM
dc.contributor.authorModolo, JR
dc.contributor.authorGottschalk, A. F.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:21:41Z
dc.date.available2014-05-20T15:21:41Z
dc.date.issued1997-01-01
dc.description.abstractThe antimicrobial susceptibility of danofloxacin was compared in vitro with ciprofloxacin against mastitogenic Staphylococcus aureus. Danofloxacin was more active than ciprofloxacin, showing minimal inhibitory concentrations (MIC90), minimal bactericidal concentrations (MBC90) and MBC/MIC ratio lower than those of ciprofloxacin. Ciprofloxacin-resistant mutants occurred at higher frequencies (greater than or equal to 10(-6)) than for danofloxacin (10(-9)).en
dc.description.affiliationUNIV ESTADUAL PAULISTA,INST BIOCIENCIAS,DEPT MICROBIOL & IMUNOL,BR-18618000 BOTUCATU,SP,BRAZIL
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA,INST BIOCIENCIAS,DEPT MICROBIOL & IMUNOL,BR-18618000 BOTUCATU,SP,BRAZIL
dc.format.extent61-64
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_issues&pid=0001-3714&lng=en&nrm=iso
dc.identifier.citationRevista de Microbiologia. São Paulo: Soc Brasileira Microbiologia, v. 28, n. 1, p. 61-64, 1997.
dc.identifier.issn0001-3714
dc.identifier.urihttp://hdl.handle.net/11449/32806
dc.identifier.wosWOS:A1997XA30400012
dc.language.isoeng
dc.publisherSoc Brasileira Microbiologia
dc.relation.ispartofRevista de Microbiologia
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectStaphylococcus aureuspt
dc.subjectdanofloxacinpt
dc.subjectciprofloxacinpt
dc.subjectsusceptibilitypt
dc.subjectresistant mutantspt
dc.titleComparative ''in vitro'' study on the susceptibility and emergence of mutants resistant to danofloxacin and ciprofloxacin among Staphylococcus aureus isolated from bovine mastitisen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rm/paboutj.htm
dcterms.rightsHolderSoc Brasileira Microbiologia
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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