Causes of resistant hypertension detected by a standardized algorithm

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dc.contributor.authorLimonta, Livia Beatriz Santos [UNESP]
dc.contributor.authorValandro, Letícia Dos Santos [UNESP]
dc.contributor.authorShiraishi, Flávio Gobis [UNESP]
dc.contributor.authorBarretti, Pasqual [UNESP]
dc.contributor.authorFranco, Roberto Jorge da Silva [UNESP]
dc.contributor.authorMartin, Luis Cuadrado [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:27:19Z
dc.date.available2014-05-27T11:27:19Z
dc.date.issued2012-12-01
dc.description.abstractResistant hypertension (RH) is characterized by blood pressure above 140 × 90 mm Hg, despite the use, in appropriate doses, of three antihypertensive drug classes, including a diuretic, or the need of four classes to control blood pressure. Resistant hypertension patients are under a greater risk of presenting secondary causes of hypertension and may be benefited by therapeutical approach for this diagnosis. However, the RH is currently little studied, and more knowledge of this clinical condition is necessary. In addition, few studies had evaluated this issue in emergent countries. Therefore, we proposed the analysis of specific causes of RH by using a standardized protocol in Brazilian patients diagnosed in a center for the evaluation and treatment of hypertension. The management of these patients was conducted with the application of a preformulated protocol which aimed at the identification of the causes of resistant hypertension in each patient through management standardization. The data obtained suggest that among patients with resistant hypertension there is a higher prevalence of secondary hypertension, than that observed in general hypertensive ones and a higher prevalence of sleep apnea as well. But there are a predominance of obesity, noncompliance with diet, and frequent use of hypertensive drugs. These latter factors are likely approachable at primary level health care, since that detailed anamneses directed to the causes of resistant hypertension are applied. © 2012 Livia Beatriz Santos Limonta et al.en
dc.description.affiliationDepartamento de Clínica Médica Faculdade de Medicina de Botucatu UNESP, Botucatu, SP
dc.description.affiliationUnespDepartamento de Clínica Médica Faculdade de Medicina de Botucatu UNESP, Botucatu, SP
dc.identifierhttp://dx.doi.org/10.1155/2012/392657
dc.identifier.citationInternational Journal of Hypertension, v. 2012.
dc.identifier.doi10.1155/2012/392657
dc.identifier.file2-s2.0-84872786335.pdf
dc.identifier.issn2090-0384
dc.identifier.issn2090-0392
dc.identifier.lattes5496411983893479
dc.identifier.lattes7095933557855151
dc.identifier.lattes4923203168446615
dc.identifier.orcid0000-0003-4979-4836
dc.identifier.scopus2-s2.0-84872786335
dc.identifier.urihttp://hdl.handle.net/11449/73854
dc.language.isoeng
dc.relation.ispartofInternational Journal of Hypertension
dc.relation.ispartofjcr1.617
dc.relation.ispartofsjr0,578
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectaliskiren
dc.subjectalpha 2 adrenergic receptor stimulating agent
dc.subjectangiotensin 2 receptor antagonist
dc.subjectbeta adrenergic receptor blocking agent
dc.subjectcalcium channel blocking agent
dc.subjectdipeptidyl carboxypeptidase inhibitor
dc.subjectdiuretic agent
dc.subjectspironolactone
dc.subjectvasodilator agent
dc.subjectadult
dc.subjectantihypertensive therapy
dc.subjectcausal attribution
dc.subjectclassification algorithm
dc.subjectdiabetic nephropathy
dc.subjectdrug treatment failure
dc.subjectfemale
dc.subjectglomerulopathy
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectpathogenesis
dc.subjectpatient attitude
dc.subjectpatient compliance
dc.subjectpolypharmacy
dc.subjectpriority journal
dc.subjectproteinuria
dc.subjectrenin angiotensin aldosterone system
dc.subjectrenovascular disease
dc.subjectresistant hypertension
dc.subjectstandardization
dc.titleCauses of resistant hypertension detected by a standardized algorithmen
dc.typeArtigo
dcterms.licensehttp://www.hindawi.com/journals/aaa/guidelines/
unesp.author.lattes5496411983893479[4]
unesp.author.lattes7095933557855151
unesp.author.lattes4923203168446615
unesp.author.orcid0000-0003-4979-4836[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentClínica Médica - FMBpt

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