Gene polymorphisms as a predictor of body weight loss after Roux-en-Y gastric bypass surgery among obese women

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dc.contributor.authorNovais, Patrícia Fátima Souza [UNESP]
dc.contributor.authorWeber, Thabata Koester [UNESP]
dc.contributor.authorLemke, Ney [UNESP]
dc.contributor.authorVerlengia, Rozangela
dc.contributor.authorCrisp, Alex Harley [UNESP]
dc.contributor.authorRasera-Junior, Irineu
dc.contributor.authorde Oliveira, Maria Rita Marques [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionMethodist University of Piracicaba (UNIMEP)
dc.contributor.institutionClínica Bariátrica
dc.date.accessioned2018-12-11T17:30:12Z
dc.date.available2018-12-11T17:30:12Z
dc.date.issued2016-11-01
dc.description.abstractThis study aimed to investigate the association between twelve gene polymorphisms and body weight loss, 12 months after Roux-en-Y gastric bypass (RYGB) surgery. Three hundred and fifty-one obese women participated in this study. The statistical software WEKA was used to identify which gene polymorphisms were potential predictors of postoperative percentage of excess weight loss (%EWL). Our results indicate that the only gene polymorphism that predicted %EWL was rs3813929, which is related to the serotonin receptor gene (5-HT2C). Therefore, the 5-HT2C gene polymorphism rs3813929 (more specifically, the TT genotype) predicted greater %EWL 12 months after RYGB surgery among female patients.en
dc.description.affiliationPost-graduate Program in Food and Nutrition São Paulo State University (UNESP)
dc.description.affiliationInstitute of Biosciences São Paulo State University (UNESP)
dc.description.affiliationPost-graduate Program in Human Movement Sciences Methodist University of Piracicaba (UNIMEP)
dc.description.affiliationClínica Bariátrica
dc.description.affiliationUnespPost-graduate Program in Food and Nutrition São Paulo State University (UNESP)
dc.description.affiliationUnespInstitute of Biosciences São Paulo State University (UNESP)
dc.format.extent724-727
dc.identifierhttp://dx.doi.org/10.1016/j.orcp.2016.07.002
dc.identifier.citationObesity Research and Clinical Practice, v. 10, n. 6, p. 724-727, 2016.
dc.identifier.doi10.1016/j.orcp.2016.07.002
dc.identifier.issn1878-0318
dc.identifier.issn1871-403X
dc.identifier.lattes7977035910952141
dc.identifier.scopus2-s2.0-84995665673
dc.identifier.urihttp://hdl.handle.net/11449/178419
dc.language.isoeng
dc.relation.ispartofObesity Research and Clinical Practice
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBariatric surgery
dc.subjectGene polymorphism
dc.subjectObesity
dc.subjectWeight loss
dc.titleGene polymorphisms as a predictor of body weight loss after Roux-en-Y gastric bypass surgery among obese womenen
dc.typeArtigo
unesp.author.lattes7977035910952141
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.departmentFísica e Biofísica - IBBpt

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Botucatu - IBB - Instituto de Biociências