Cytotoxic and genotoxic effects of silver nanoparticle/carboxymethyl cellulose on Allium cepa

Página do item simplificado
dc.contributor.authorBecaro, Aline A.
dc.contributor.authorSiqueira, Maria Célia
dc.contributor.authorPuti, Fernanda C.
dc.contributor.authorde Moura, Marcia Regina [UNESP]
dc.contributor.authorCorrea, Daniel S.
dc.contributor.authorMarconcini, José Manoel
dc.contributor.authorMattoso, Luiz H. C.
dc.contributor.authorFerreira, Marcos David
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:47:57Z
dc.date.available2018-12-11T16:47:57Z
dc.date.issued2017-07-01
dc.description.abstractSeveral mutagenic agents may be present in substances released in the environment, which may cause serious environmental impacts. Among these substances, there is a special concern regarding the widespread use of silver nanoparticles (AgNP) in several products due to their widely known bactericidal properties, including in the medical field and the food industry (e.g., active packaging). The assessment of the effects of AgNP released in the environment, having different concentrations, sizes, and being associated or not to other types of materials, including polymers, is therefore essential. In this research, the objective was to evaluate the genotoxic and cytotoxic effects of AgNP (size range between 2 and 8 nm) on root meristematic cells of Allium cepa (A. cepa). Tests were carried out in the presence of colloidal solution of AgNP and AgNP mixed with carboxymethylcellulose (CMC), using distinct concentrations of AgNP. As a result, when compared to control samples, AgNP induced a mitotic index decrease and an increase of chromosomal aberration number for two studied concentrations. When AgNP was in the presence of CMC, no cytotoxic potential was verified, but only the genotoxic potential for AgNP dispersion having concentration of 12.4 ppm.en
dc.description.affiliationPrograma de Pós-Graduação em Biotecnologia (PPGBiotec) Centro de Ciências Exatas e Tecnologia Universidade Federal de São Carlos (UFSCar)
dc.description.affiliationLaboratório Nacional de Nanotecnologia para o Agronegócio (LNNA) EMBRAPA Instrumentação
dc.description.affiliationPrograma de Pós-Graduação em Química (PPGQ) Centro de Ciências Exatas e Tecnologia Universidade Federal de São Carlos (UFSCar)
dc.description.affiliationDepartamento de Física e Química UNESP
dc.description.affiliationUnespDepartamento de Física e Química UNESP
dc.identifierhttp://dx.doi.org/10.1007/s10661-017-6062-8
dc.identifier.citationEnvironmental Monitoring and Assessment, v. 189, n. 7, 2017.
dc.identifier.doi10.1007/s10661-017-6062-8
dc.identifier.file2-s2.0-85021353155.pdf
dc.identifier.issn1573-2959
dc.identifier.issn0167-6369
dc.identifier.scopus2-s2.0-85021353155
dc.identifier.urihttp://hdl.handle.net/11449/169869
dc.language.isoeng
dc.relation.ispartofEnvironmental Monitoring and Assessment
dc.relation.ispartofsjr0,589
dc.relation.ispartofsjr0,589
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAllium cepa
dc.subjectCarboxymethylcellulose
dc.subjectChromosomal aberration
dc.subjectMitotic test
dc.subjectSilver nanoparticles
dc.titleCytotoxic and genotoxic effects of silver nanoparticle/carboxymethyl cellulose on Allium cepaen
dc.typeArtigo

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
2-s2.0-85021353155.pdf
Tamanho:
1.15 MB
Formato:
Adobe Portable Document Format
Descrição:
Baixar

Coleções

Artigos