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Structure and antimycobacterial activity of the novel organometallic [Pd(C-bzan)(SCN)(dppp)] compound

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dc.contributor.authorFerreira, Janaina G. [UNESP]
dc.contributor.authorStevanato, Alessandra [UNESP]
dc.contributor.authorSantana, Anderson M.
dc.contributor.authorMauro, Antonio Eduardo [UNESP]
dc.contributor.authorNetto, Adelino Vieira de Godoy [UNESP]
dc.contributor.authorFrem, Regina Célia Galvão [UNESP]
dc.contributor.authorPavan, Fernando R. [UNESP]
dc.contributor.authorLeite, Clarice Q. F. [UNESP]
dc.contributor.authorSantos, Regina H. A.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Mato Grosso (UFMT)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:24:16Z
dc.date.available2014-05-20T13:24:16Z
dc.date.issued2012-09-01
dc.description.abstractThe organometallic compound [Pd(C-bzan)(SCN)(dppp)] {bzan = N-benzylideneaniline, dppp = 1,3-bis(diphenylphosphino)propane} was synthesized and characterized by elemental analyses, infrared and H-1 and P-31(H-1) NMR spectroscopies. The crystal and molecular structures of the title complex were determined by single-crystal X-ray diffraction techniques. In vitro antimycobacterial evaluation demonstrated that the compound [Pd(C-bzan)(SCN)(dppp)] displayed a MIC of 5.15 mu M, which is superior than those values found for some commonly used anti-TB drugs and other Pd(II) complexes. (C) 2012 Elsevier B.V. All rights reserved.en
dc.description.affiliationUNESP Univ Estadual Paulista, Inst Quim Araraquara, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationICET UFMT, Inst Ciencias Exatas & Terra, BR-78060900 Cuiaba, MT, Brazil
dc.description.affiliationUniv São Paulo, Inst Quim São Carlos, São Carlos, SP, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Fac Ciencias Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Inst Quim Araraquara, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Fac Ciencias Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent63-66
dc.identifierhttp://dx.doi.org/10.1016/j.inoche.2012.06.007
dc.identifier.citationInorganic Chemistry Communications. Amsterdam: Elsevier B.V., v. 23, p. 63-66, 2012.
dc.identifier.doi10.1016/j.inoche.2012.06.007
dc.identifier.issn1387-7003
dc.identifier.lattes3300223970814448
dc.identifier.lattes7927677053650819
dc.identifier.orcid0000-0002-0057-7964
dc.identifier.urihttp://hdl.handle.net/11449/7483
dc.identifier.wosWOS:000308271900015
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofInorganic Chemistry Communications
dc.relation.ispartofjcr1.810
dc.relation.ispartofsjr0,430
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectOrganometallic Pd(II) compounden
dc.subject1,3-bis(Diphenylphosphino)propaneen
dc.subjectMycobacterium tuberculosisen
dc.titleStructure and antimycobacterial activity of the novel organometallic [Pd(C-bzan)(SCN)(dppp)] compounden
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
relation.isDepartmentOfPublication5004bcab-94af-4939-b980-091ae9d0a19e
relation.isDepartmentOfPublication.latestForDiscovery5004bcab-94af-4939-b980-091ae9d0a19e
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes3300223970814448[4]
unesp.author.lattes7927677053650819[5]
unesp.author.orcid0000-0002-0057-7964[5]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentCiências Biológicas - FCFpt
unesp.departmentQuímica Inorgânica - IQARpt

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Araraquara - IQAR - Instituto de Química
Araraquara - FCF - Faculdade de Ciências Farmacêuticas