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Effect of vaccination and the immunomodulators bacillus of Calmette-Guerin, Avridine and Propionibacterium acnes on rabies in mice

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dc.contributor.authorMegid, Jane [UNESP]
dc.contributor.authorPeracolli, MTS
dc.contributor.authorCuri, P. R.
dc.contributor.authorZanetti, C. R.
dc.contributor.authorCabrera, W. H.
dc.contributor.authorVassao, R.
dc.contributor.authorIto, F. H.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionInst Pasteur
dc.contributor.institutionInstituto Butantan
dc.date.accessioned2014-05-20T13:38:11Z
dc.date.available2014-05-20T13:38:11Z
dc.date.issued1998-10-01
dc.description.abstractResponses: of vaccination and treatment to immunomodulators against rabies in mice were evaluated through macrophage inhibition factor (MIF), intra-pad inoculation (IPI) and serum neutralization (SN) tests and by the detection of gamma-interferon (IFN-gamma). Onco-BCG, Avridine and Propionibacterium acnes were administered to groups of mice. Higher survival rates were found in animals treated with P. acnes. Lower levels of IFN-gamma were observed in the groups of infected and vaccinated mice. The IPI was not effective on detecting the response of delayed-type hypersensitivity. Vaccine induced in the infected animals a more intense response to MIF reaction. (C) 1998 Elsevier B.V. Ltd. All rights reserved.en
dc.description.affiliationUNESP, FMVZ, Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.description.affiliationUNESP, Inst Biosci, Dept Immunol & Microbiol, Botucatu, SP, Brazil
dc.description.affiliationInst Pasteur, São Paulo, Brazil
dc.description.affiliationInst Butantan, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, FMVZ, Dept Prevent Vet Med & Anim Hlth, São Paulo, Brazil
dc.description.affiliationUnespUNESP, FMVZ, Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP, Inst Biosci, Dept Immunol & Microbiol, Botucatu, SP, Brazil
dc.format.extent305-318
dc.identifierhttp://dx.doi.org/10.1016/S0147-9571(98)00005-8
dc.identifier.citationComparative Immunology Microbiology and Infectious Diseases. Oxford: Pergamon-Elsevier B.V., v. 21, n. 4, p. 305-318, 1998.
dc.identifier.doi10.1016/S0147-9571(98)00005-8
dc.identifier.issn0147-9571
dc.identifier.urihttp://hdl.handle.net/11449/13245
dc.identifier.wosWOS:000075804400006
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofComparative Immunology Microbiology and Infectious Diseases
dc.relation.ispartofjcr1.920
dc.relation.ispartofsjr0,877
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectrabiespt
dc.subjectimmunomodulatorspt
dc.subjectcellular immunitypt
dc.subjecthumoral immunitypt
dc.subjectMIFpt
dc.subject-INTERFERONpt
dc.subjectmicept
dc.titleEffect of vaccination and the immunomodulators bacillus of Calmette-Guerin, Avridine and Propionibacterium acnes on rabies in miceen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.orcid0000-0002-6540-7157[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
unesp.departmentHigiene Veterinária e Saúde Pública - FMVZpt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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Botucatu - FMVZ - Faculdade de Medicina Veterinária e Zootecnia
Botucatu - IBB - Instituto de Biociências