Evaluation of argyrophilic nucleolar organizer regions in oral tumor progression
| dc.contributor.author | Spolidorio, L. C. | |
| dc.contributor.author | Neves, K. A. | |
| dc.contributor.author | Soares, C. P. | |
| dc.contributor.author | Spolidorio, D. M.P. | |
| dc.contributor.author | Basso, M. F.M. | |
| dc.contributor.author | Malavazzi, I. | |
| dc.contributor.author | Almeida, O. P. | |
| dc.contributor.institution | Universidade de São Paulo (USP) | |
| dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | |
| dc.date.accessioned | 2022-04-29T08:42:46Z | |
| dc.date.available | 2022-04-29T08:42:46Z | |
| dc.date.issued | 2002-12-18 | |
| dc.description.abstract | The aim of this study was to compare the presence of nucleolar organizer regions (NORs) in normal oral mucosa, dysplasia and microinvasive carcinoma. All histological specimens were reviewed according to the modified classification and staging system for oral leukoplakia described by van-der-Waal et al. [Oral Oncol. 36 (2000) 264]. NOR quantification was performed with an image analyzer after staining by the argyrophilic nucleolar region technique. The morphometric results were statistically different for normal mucosa, dysplasia and microinvasive carcinoma. It was concluded that an increase of NOR activity follows the disease progression and may reflect the degree of cellular proliferation and malignancy. © 2002 Elsevier Science Ltd. All rights reserved. | en |
| dc.description.affiliation | Department of Oral Pathology Araraquara Dental School University of São Paulo State, Rua Humaitá, 1680 CEP, 14801-903 Araraquara | |
| dc.description.affiliation | Department of Clinical Analysis Faculty of Pharmaceutical Sciences University of São Paulo State, Rua Expedicionários do Brasil, 1621 CEP, 14801-902 Araraquara | |
| dc.description.affiliation | Department of Oral Pathology Piracicaba Dental School UNICAMP, Av Limeira s/n, Piracicaba | |
| dc.format.extent | 605-608 | |
| dc.identifier | http://dx.doi.org/10.1016/S0968-4328(02)00031-8 | |
| dc.identifier.citation | Micron, v. 33, n. 7-8, p. 605-608, 2002. | |
| dc.identifier.doi | 10.1016/S0968-4328(02)00031-8 | |
| dc.identifier.issn | 0968-4328 | |
| dc.identifier.scopus | 2-s2.0-0036446038 | |
| dc.identifier.uri | http://hdl.handle.net/11449/230921 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Micron | |
| dc.source | Scopus | |
| dc.subject | Argyrophilic nucleolar regions | |
| dc.subject | Dysplasia | |
| dc.subject | Oral carcinoma | |
| dc.subject | Oral mucosa | |
| dc.subject | Tumor progression | |
| dc.title | Evaluation of argyrophilic nucleolar organizer regions in oral tumor progression | en |
| dc.type | Artigo | pt |
| dspace.entity.type | Publication | |
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| unesp.campus | Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquara | pt |
| unesp.department | Análises Clínicas - FCF | pt |
| unesp.department | Fisiologia e Patologia - FOAR | pt |