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Low levels of taurine introgression in the current Brazilian Nelore and Gir indicine cattle populations

dc.contributor.authorO'Brien, Ana M. Perez
dc.contributor.authorHoeler, Daniela
dc.contributor.authorBoison, Solomon A.
dc.contributor.authorMilanesi, Marco
dc.contributor.authorBomba, Lorenzo
dc.contributor.authorUtsunomiya, Yuri T. [UNESP]
dc.contributor.authorCarvalheiro, Roberto [UNESP]
dc.contributor.authorNeves, Haroldo H. R. [UNESP]
dc.contributor.authorSilva, Marcos V. B. da
dc.contributor.authorVanTassell, Curtis P.
dc.contributor.authorSonstegard, Tad S.
dc.contributor.authorMeszaros, Gabor
dc.contributor.authorAjmone-Marsan, Paolo
dc.contributor.authorGarcia, Fernando [UNESP]
dc.contributor.authorSoelkner, Johann
dc.contributor.institutionUniv Nat Resources &Life Sci BOKU
dc.contributor.institutionUniv Cattolica Sacro Cuore Piacenza
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.institutionUSDA ARS
dc.date.accessioned2015-10-22T06:27:55Z
dc.date.available2015-10-22T06:27:55Z
dc.date.issued2015-04-17
dc.description.abstractBackground: Nelore and Gir are the two most important indicine cattle breeds for production of beef and milk in Brazil. Historical records state that these breeds were introduced in Brazil from the Indian subcontinent, crossed to local taurine cattle in order to quickly increase the population size, and then backcrossed to the original breeds to recover indicine adaptive and productive traits. Previous investigations based on sparse DNA markers detected taurine admixture in these breeds. High-density genome-wide analyses can provide high-resolution information on the genetic composition of current Nelore and Gir populations, estimate more precisely the levels and nature of taurine introgression, and shed light on their history and the strategies that were used to expand these breeds.Results: We used the high-density Illumina BovineHD BeadChip with more than 777 K single nucleotide polymorphisms (SNPs) that were reduced to 697 115 after quality control filtering to investigate the structure of Nelore and Gir populations and seven other worldwide populations for comparison. Multidimensional scaling and model-based ancestry estimation clearly separated the indicine, European taurine and African taurine ancestries. The average level of taurine introgression in the autosomal genome of Nelore and Gir breeds was less than 1% but was 9% for the Brahman breed. Analyses based on the mitochondrial SNPs present in the Illumina BovineHD BeadChip did not clearly differentiate taurine and indicine haplotype groupings.Conclusions: The low level of taurine ancestry observed for both Nelore and Gir breeds confirms the historical records of crossbreeding and supports a strong directional selection against taurine haplotypes via backcrossing. Random sampling in production herds across the country and subsequent genotyping would be useful for a more complete view of the admixture levels in the commercial Nelore and Gir populations.en
dc.description.affiliationDepartment of Sustainable Agricultural Systems, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria
dc.description.affiliationUniversità Cattolica del Sacro Cuore di Piacenza, Institute of Zootechnica and Biodiversity and Ancient DNA Research Center - BioDNA, Piacenza, Italy
dc.description.affiliationEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Gado de Leite, Juiz de Fora, MG, Brazil
dc.description.affiliationUnited States Department of Agriculture - Agricultural Research Service, Bovine Functional Genomics Laboratory, Beltsville, MD, USA
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Agrária e Veterinárias, Jaboticabal, SP, Brazil
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP) - Faculdade de Medicina Veterinária de Araçatuba, Araçatuba, SP, Brazil
dc.description.sponsorshipEuropean Science Foundation
dc.description.sponsorshipAdvances in Farm Animal Genomic Resources project
dc.description.sponsorshipUSDA-ARS
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdUSDA-ARS: 1265-31000-104-00D
dc.description.sponsorshipIdCNPq: 560922/2010-8
dc.description.sponsorshipIdCNPq: 483590/2010-0
dc.description.sponsorshipIdFAPESP: 2014/01095-8
dc.description.sponsorshipIdFAPESP: 2010/52030-2
dc.format.extent1-7
dc.identifierhttp://www.gsejournal.org/content/47/1/31
dc.identifier.citationGenetics Selection Evolution. London: Biomed Central Ltd, v. 47, p. 1-7, 2015.
dc.identifier.doi10.1186/s12711-015-0109-5
dc.identifier.fileWOS000353019200003.pdf
dc.identifier.issn0999-193X
dc.identifier.urihttp://hdl.handle.net/11449/129674
dc.identifier.wosWOS:000353019200003
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofGenetics Selection Evolution
dc.relation.ispartofjcr3.743
dc.rights.accessRightsAcesso abertopt
dc.sourceWeb of Science
dc.titleLow levels of taurine introgression in the current Brazilian Nelore and Gir indicine cattle populationsen
dc.typeArtigopt
dcterms.rightsHolderBiomed Central Ltd
dspace.entity.typePublication
relation.isOrgUnitOfPublication1f8041b8-563c-4766-90b9-4dd9c0101666
relation.isOrgUnitOfPublication.latestForDiscovery1f8041b8-563c-4766-90b9-4dd9c0101666
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária, Araçatubapt

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