Publicação: Microbiological assay for cefoxitin sodium in dosage form
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Aoac International
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A microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 mu g/mL. The validation showed that the method was linear (r = 0.9998), precise (RSD 0.81%), and accurate. It was concluded that the microbiological assay is satisfactory for quantitation of cefoxitin sodium in injectables.
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Journal of Aoac International. Gaithersburg: Aoac International, v. 90, n. 2, p. 452-455, 2007.
