Publicação:
Adverse drug reaction as cause of hospital admission of elderly people: a pilot study

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dc.contributor.authorVarallo, Fabiana R. [UNESP]
dc.contributor.authorLima, Marcos F.R. [UNESP]
dc.contributor.authorGalduróz, José C.F.
dc.contributor.authorMastroianni, Patricia de Carvalho [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2014-05-27T11:25:51Z
dc.date.available2014-05-27T11:25:51Z
dc.date.issued2011-04-18
dc.description.abstractThe objective of this study was to estimate the prevalence of adverse drug reactions (ADR) related to hospital admission of elderly people, identifying the use of potentially inappropriate medication (PIM), the ADR and the risk factors associated with the hospitalization. A cross-sectional study was conducted in a private hospital of São Paulo State, Brazil. All patients aged ≥ 60 years, admitted in the general practice ward in May 2006 were interviewed about the drugs used and the symptoms/complaints that resulted in hospitalization. More than a half (54.5 %) of elderly hospitalizations were related with ADR. The therapeutic classes involved with ADR were: cardiovascular (37.7 %), central nervous (34.6 %) and respiratory (5.7 %). The ADR observed were disorders in circulatory (28.4 %), digestive (20.0 %) and respiratory (18.9 %) tracts. 27 elderly had made PIM and in 20 of them this was the cause of hospitalization. Polypharmacy was an ADR risk factor (p = 0.021).These data allows the healthcare professionals upgrade, qualifying them in pharmcovigilance.en
dc.description.affiliationDepartment of Drugs and Medications School of Pharmaceutical Sciences Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP, Araraquara
dc.description.affiliationSchool of Pharmaceutical Science Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP, Araraquara
dc.description.affiliationDepartment of Psychobiology Escola Paulista de Medicina Universidade Federal de São Paulo, UNIFESP, São Paulo
dc.description.affiliationUnespDepartment of Drugs and Medications School of Pharmaceutical Sciences Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP, Araraquara
dc.description.affiliationUnespSchool of Pharmaceutical Science Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP, Araraquara
dc.format.extent347
dc.identifierhttp://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_1_19.pdf
dc.identifier.citationLatin American Journal of Pharmacy, v. 30, n. 2, p. 347-, 2011.
dc.identifier.issn0326-2383
dc.identifier.lattes4160558780902988
dc.identifier.orcid0000-0001-8467-7278
dc.identifier.scopus2-s2.0-79953838949
dc.identifier.urihttp://hdl.handle.net/11449/72389
dc.identifier.wosWOS:000291136700019
dc.language.isoeng
dc.relation.ispartofLatin American Journal of Pharmacy
dc.relation.ispartofjcr0.401
dc.relation.ispartofsjr0,152
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAdverse drug reaction
dc.subjectElderly people
dc.subjectHospital admission
dc.subjectUse of drugs
dc.subjectacetylsalicylic acid
dc.subjectatenolol
dc.subjectbromazepam
dc.subjectcaptopril
dc.subjectclopidogrel
dc.subjectdipyrone
dc.subjectenalapril
dc.subjectnitric acid derivative
dc.subjectomeprazole
dc.subjectpropatilnitrate
dc.subjectsimvastatin
dc.subjectunclassified drug
dc.subjectabdominal pain
dc.subjectadult
dc.subjectadverse drug reaction
dc.subjectaged
dc.subjectallergic reaction
dc.subjectangina pectoris
dc.subjectangioneurotic edema
dc.subjectarthralgia
dc.subjectasthma
dc.subjectattention deficit disorder
dc.subjectbleeding
dc.subjectBrazil
dc.subjectbronchospasm
dc.subjectcardiovascular disease
dc.subjectcentral nervous system disease
dc.subjectconstipation
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectdigestive system function disorder
dc.subjectdigestive system ulcer
dc.subjectdizziness
dc.subjectdyspepsia
dc.subjectdyspnea
dc.subjectgastrointestinal disease
dc.subjectgastrointestinal hemorrhage
dc.subjectgeriatric patient
dc.subjectheart arrhythmia
dc.subjectheart failure
dc.subjecthospital admission
dc.subjecthuman
dc.subjecthypertension
dc.subjecthypotension
dc.subjectlung disease
dc.subjectlung edema
dc.subjectlung insufficiency
dc.subjectmajor clinical study
dc.subjectmuscle weakness
dc.subjectmyalgia
dc.subjectnausea
dc.subjectneuralgia
dc.subjectorthostatic hypotension
dc.subjectpilot study
dc.subjectpneumonia
dc.subjectpolypharmacy
dc.subjectprescription
dc.subjectprevalence
dc.subjectprivate hospital
dc.subjectrespiratory tract disease
dc.subjectrisk factor
dc.subjectsomnolence
dc.subjectsymptomatology
dc.subjectsyncope
dc.subjecttachycardia
dc.subjectvertigo
dc.subjectvisual disorder
dc.subjectvomiting
dc.titleAdverse drug reaction as cause of hospital admission of elderly people: a pilot studyen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes4160558780902988[4]
unesp.author.orcid0000-0001-8467-7278[4]
unesp.author.orcid0000-0002-2710-9693[3]
unesp.author.orcid0000-0003-4016-1442[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Coleções

Araraquara - FCF - Faculdade de Ciências Farmacêuticas