Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens
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The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybee (Apis mellifera) venom, both collected in the State of Sb Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct- and indirect-acting mutagens. EEP had inhibitory effect (in an ascending order) on the mutagenicity power of daunomycin (TA102), benzo(a)pyrene (TA100), and aflatoxin B-1(TA98) and the venom acted against the mutagenicity of 4-nitro-o-phenylenediamine (TA98) and daunomycin (TA102). (C) 1999 Wiley-Liss, Inc.
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Teratogenesis Carcinogenesis and Mutagenesis. New York: Wiley-liss, v. 19, n. 6, p. 403-413, 1999.
