Publicação: Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate
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2012-01-01
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Because of the growing concerns regarding fluoride ingestion by young children and dental fluorosis, it is necessary to develop new dentifrices. Objective: The aim ofthis study was to evaluate the effect of dentifrices with calcium citrate (Cacit) and sodium trimetaphosphate (TMP) on enamel demineralization. Material and Methods: Enamel blocks (n=70), previously selected through surface hardness analysis, were submitted to daily treatment with dentifrices diluted in artificial saliva and to a pH-cycling model. The fluoride concentration in dentifrices was 0, 250, 450, 550, 1,000 and 1,100 μg F/g. Crest™ was used as a positive control (1,100 μg F/g). Cacit (0.25%) and TMP (0.25%) were added to dentifrices with 450 and 1,000 μg F/g. Surface hardness was measured again and integrated loss of subsurface hardness and fluoride concentration in enamel were calculated. Parametric and correlation tests were used to determine difference (p<0.05) and dose-response relationship between treatments. Results: The addition of Cacit and TMP did not provide a higher fluoride concentration in enamel, however it reduced (p<0.05) mineral loss when compared to other dentifrices; the dentifrice with Cacit and TMP and a low fluoride concentration presented similar results when compared to a dentifrice with 1,100 μg F/g (p>0.05). Conclusions: Dentifrices with 450 and 1,000 μg F/g, Cacit and TMP were as effective as a gold standard one.
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Journal of Applied Oral Science, v. 20, n. 1, p. 94-98, 2012.
