Publicação: Esparfloxacino e as fluorquinolonas: Uma revisao de sua classificacao, atividade antibacteriana, mecanismo de acao, caracteristicas farmacocineticas, tolerabilidade e perspectivas farmaceuticas
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Resumo
A revision was accomplished in the literature on the quinolones, antibacterial class that presents wide action spectrum, focusing, mainly, the sparfloxacin, third generation fluorquinolone which has potente activity against Gram positive organisms, including Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus (MRSA), Gram negative organisms, Legionelia spp, Mycoplasma spp, Chlamydia spp and Mycobacterium spp, including multidrug resistant organisms.
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Antibacterial activity, Fluoroquinolones, Quinolones, Sparfloxacin, antiinfective agent, ciprofloxacin, fleroxacin, irloxacin, levofloxacin, lomefloxacin, nadifloxacin, nalidixic acid, norfloxacin, ofloxacin, pefloxacin, pefloxacin mesilate, pipemidic acid, quinoline derived antiinfective agent, quinolone derivative, rufloxacin, sparfloxacin, trovafloxacin, antibacterial activity, drug distribution, drug mechanism, drug structure, drug tolerability, flatulence, gastrointestinal symptom, Gram positive bacterium, human, nonhuman, review, structure activity relation
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Português
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Revista de Ciencias Farmaceuticas, v. 20, n. 2, p. 301-333, 1999.
