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MS222 does not induce primary DNA damage in fish

dc.contributor.authorBarreto, R. E. [UNESP]
dc.contributor.authorGontijo, A. M M C
dc.contributor.authorAlves-de-Lima, R. O. [UNESP]
dc.contributor.authorRaymundi, V. C. [UNESP]
dc.contributor.authorPinhal, D. [UNESP]
dc.contributor.authorReyes, V. A V [UNESP]
dc.contributor.authorVolpato, G. L. [UNESP]
dc.contributor.authorSalvadori, Daisy Maria Favero [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionInstitut Pasteur
dc.date.accessioned2014-05-27T11:22:26Z
dc.date.available2014-05-27T11:22:26Z
dc.date.issued2007-04-01
dc.description.abstractThe genotoxicity of the anaesthetic MS222 (tricaine) was analysed in fish under both in vivo and in vitro conditions. Based on results of the single cell gel/Comet assay, MS222 had no direct genotoxic effect on the experimental fish, indicating that MS222 does not induce primary DNA damage. These results suggest that the use of this important anaesthetic in aquaculture can be considered to be safe in terms of genotoxicity. © Springer Science+Business Media, Inc. 2007.en
dc.description.affiliationDepartamento de Fisiologia Instituto de Biociências UNESP, Rubião Jr. s/n, 18618-000 Botucatu, SP
dc.description.affiliationUnité de Biologie des Interactions Hôte-Parasite Institut Pasteur, Paris
dc.description.affiliationTOXICAN - Núcleo de Avaliação Toxicogenética e Cancerígena Departamento de Patologia UNESP, 18618-000 Botucatu, SP
dc.description.affiliationUnespDepartamento de Fisiologia Instituto de Biociências UNESP, Rubião Jr. s/n, 18618-000 Botucatu, SP
dc.description.affiliationUnespTOXICAN - Núcleo de Avaliação Toxicogenética e Cancerígena Departamento de Patologia UNESP, 18618-000 Botucatu, SP
dc.format.extent163-168
dc.identifierhttp://dx.doi.org/10.1007/s10499-007-9073-6
dc.identifier.citationAquaculture International, v. 15, n. 2, p. 163-168, 2007.
dc.identifier.doi10.1007/s10499-007-9073-6
dc.identifier.issn0967-6120
dc.identifier.issn1573-143X
dc.identifier.lattes3363114201357959
dc.identifier.lattes5051118752980903
dc.identifier.scopus2-s2.0-34247217248
dc.identifier.urihttp://hdl.handle.net/11449/69587
dc.language.isoeng
dc.relation.ispartofAquaculture International
dc.relation.ispartofjcr1.283
dc.relation.ispartofsjr0,591
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAnaesthetic tricaine (ethyl meta-aminobenzoate)
dc.subjectDNA damage
dc.subjectMethane sulfonate salt
dc.subjectMS222
dc.subjectSingle cell gel (SCG)/Comet assay
dc.subjectStressful practices in aquaculture
dc.subjectaquaculture
dc.subjectDNA
dc.subjectfish
dc.subjectgenotoxicity
dc.subjectmethane
dc.titleMS222 does not induce primary DNA damage in fishen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
dspace.entity.typePublication
unesp.author.lattes3363114201357959
unesp.author.lattes5051118752980903
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentPatologia - FMBpt
unesp.departmentFisiologia - IBBpt

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