MS222 does not induce primary DNA damage in fish
dc.contributor.author | Barreto, R. E. [UNESP] | |
dc.contributor.author | Gontijo, A. M M C | |
dc.contributor.author | Alves-de-Lima, R. O. [UNESP] | |
dc.contributor.author | Raymundi, V. C. [UNESP] | |
dc.contributor.author | Pinhal, D. [UNESP] | |
dc.contributor.author | Reyes, V. A V [UNESP] | |
dc.contributor.author | Volpato, G. L. [UNESP] | |
dc.contributor.author | Salvadori, Daisy Maria Favero [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Institut Pasteur | |
dc.date.accessioned | 2014-05-27T11:22:26Z | |
dc.date.available | 2014-05-27T11:22:26Z | |
dc.date.issued | 2007-04-01 | |
dc.description.abstract | The genotoxicity of the anaesthetic MS222 (tricaine) was analysed in fish under both in vivo and in vitro conditions. Based on results of the single cell gel/Comet assay, MS222 had no direct genotoxic effect on the experimental fish, indicating that MS222 does not induce primary DNA damage. These results suggest that the use of this important anaesthetic in aquaculture can be considered to be safe in terms of genotoxicity. © Springer Science+Business Media, Inc. 2007. | en |
dc.description.affiliation | Departamento de Fisiologia Instituto de Biociências UNESP, Rubião Jr. s/n, 18618-000 Botucatu, SP | |
dc.description.affiliation | Unité de Biologie des Interactions Hôte-Parasite Institut Pasteur, Paris | |
dc.description.affiliation | TOXICAN - Núcleo de Avaliação Toxicogenética e Cancerígena Departamento de Patologia UNESP, 18618-000 Botucatu, SP | |
dc.description.affiliationUnesp | Departamento de Fisiologia Instituto de Biociências UNESP, Rubião Jr. s/n, 18618-000 Botucatu, SP | |
dc.description.affiliationUnesp | TOXICAN - Núcleo de Avaliação Toxicogenética e Cancerígena Departamento de Patologia UNESP, 18618-000 Botucatu, SP | |
dc.format.extent | 163-168 | |
dc.identifier | http://dx.doi.org/10.1007/s10499-007-9073-6 | |
dc.identifier.citation | Aquaculture International, v. 15, n. 2, p. 163-168, 2007. | |
dc.identifier.doi | 10.1007/s10499-007-9073-6 | |
dc.identifier.issn | 0967-6120 | |
dc.identifier.issn | 1573-143X | |
dc.identifier.lattes | 3363114201357959 | |
dc.identifier.lattes | 5051118752980903 | |
dc.identifier.scopus | 2-s2.0-34247217248 | |
dc.identifier.uri | http://hdl.handle.net/11449/69587 | |
dc.language.iso | eng | |
dc.relation.ispartof | Aquaculture International | |
dc.relation.ispartofjcr | 1.283 | |
dc.relation.ispartofsjr | 0,591 | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Scopus | |
dc.subject | Anaesthetic tricaine (ethyl meta-aminobenzoate) | |
dc.subject | DNA damage | |
dc.subject | Methane sulfonate salt | |
dc.subject | MS222 | |
dc.subject | Single cell gel (SCG)/Comet assay | |
dc.subject | Stressful practices in aquaculture | |
dc.subject | aquaculture | |
dc.subject | DNA | |
dc.subject | fish | |
dc.subject | genotoxicity | |
dc.subject | methane | |
dc.title | MS222 does not induce primary DNA damage in fish | en |
dc.type | Artigo | |
dcterms.license | http://www.springer.com/open+access/authors+rights | |
dspace.entity.type | Publication | |
unesp.author.lattes | 3363114201357959 | |
unesp.author.lattes | 5051118752980903 | |
unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatu | pt |
unesp.campus | Universidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatu | pt |
unesp.department | Patologia - FMB | pt |
unesp.department | Fisiologia - IBB | pt |