Development of an oral mucosa equivalent using a porcine dermal matrix
Abstract
We evaluated the suitability of a porcine acellular dermal matrix for the development of a 3-dimensional oral mucosal equivalent using an ex vivo-produced oral mucosal equivalent (EVPOME). Oral keratinocytes were seeded in a submerged model, and then in an air-liquid interphase model, using Transwell® inserts. EVPOME showed good cell viability and increased glucose consumption over time. Histological evaluation showed that stratified differentiated epithelium had formed in all matrices.
How to cite this document
Basso, F. G. et al. Development of an oral mucosa equivalent using a porcine dermal matrix. British Journal of Oral and Maxillofacial Surgery, v. 55, n. 3, p. 308-311, 2017. Available at: <http://hdl.handle.net/11449/173665>.
Language
English
