The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
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Data
2020-12-01
Autores
Simoes, Luciana Senna
Castro Sasahara, Tais Harumi de
Favaron, Phelipe Oliveira
Leal, Leonardo Martins
Oliveira, Fabricio Singaretti de [UNESP]
Fratini, Paula
Berger, Trish
Fernandes Machado, Marcia Rita [UNESP]
Miglino, Maria Angelica
Título da Revista
ISSN da Revista
Título de Volume
Editor
Soc Chilena Anatomia
Resumo
The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.
Descrição
Palavras-chave
Gonadal, Toxic, Spermatogenesis
Como citar
International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.