Prevalence and genetic characterization of Dientamoeba fragilis in asymptomatic children attending daycare centers
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Data
2021-01-01
Autores
Oliveira-Arbex, Ana Paula [UNESP]
David, Erica Boarato [UNESP]
Caccio, Simone Mario
Branco da Fonseca, Catia Regina [UNESP]
Martin, Joelma Goncalves [UNESP]
Kurokawa, Cilmery Suemi [UNESP]
Tosini, Fabio
Souza-Neto, Jayme Augusto [UNESP]
Guimaraes, Semiramis [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Inst Medicina Tropical Sao Paulo
Resumo
In order to provide additional data on the prevalence and genetic diversity of Dientantoeba fragilis in human populations, we conducted a study in children from low-income communities in Sao Paulo State. Brazil. Fecal samples from daycare center attendees up to 6 years old (n=156) and staff members (n=18) were submitted to PCR and sequencing of D. fragilis as well as to microscopic examination for the presence of other intestinal parasites. All children assessed were asymptomatic and 10.3% (16/156) were positive for D. fragilis. No worker was found to be positive. An association between Dientamoeba and coinfection with other intestinal parasites was observed. Concerning the genetic diversity, 14 and only two isolates were genotype 1 and genotype 2, respectively. Our findings outline interesting aspects: (1) asymptomatic children as carriers of Dientamoeba in communities in which environmental conditions ensure parasite transmission and. (2) association between Dientamoeba infection in young children and coinfection with other enteric parasites, reinforcing its transmission via the fecal-oral route.
Descrição
Palavras-chave
Dientamoeba fragilis, Prevalence, Children, PCR, Genotypes
Como citar
Revista Do Instituto De Medicina Tropical De Sao Paulo. Sao Paulo: Inst Medicina Tropical Sao Paulo, v. 63, 6 p., 2021.