Eficácia da pré-medicação com fármacos anti-inflamatórios não esteroidais no auxílio ao controle da dor pós tratamento endodôntico: uma revisão sistemática.
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Data
2021-01-29
Autores
Meireles, Lucas de Oliveira [UNESP]
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Editor
Universidade Estadual Paulista (Unesp)
Resumo
Objetivo: O objetivo desta revisão sistemática foi avaliar a eficácia da pré-medicação de fármacos anti-inflamatórios não esteroidais em pacientes submetidos a tratamento endodôntico quanto ao risco de dor pós-operatória. Método: Foi realizada uma busca nas bases de dados Medline, não havendo restrição quanto ao ano ou idioma da publicação. Ensaios clínicos randomizados que avaliaram a eficácia da pré-medicação com anti-inflamatórios não esteroidais na redução da dor pós-operatória foram incluídos nesta revisão sistemática. Uma meta-análise foi realizada para a comparação entre o grupo de anti-inflamatórios não esteroidais e o grupo placebo nos períodos de 6 a 8 horas e 24 horas após o tratamento endodôntico. Resultados: Um total de 1809 estudos foram identificados e apenas onze estudos atenderam aos critérios de elegibilidade, sendo sete deles para a meta-análise. Houve uma diferença significativa entre o grupo de anti-inflamatórios em relação ao grupo placebo no período de 6 a 8 horas após o tratamento endodôntico, porém após 24 horas a diferença foi quase nula quanto a presença de dor. Conclusão: Os resultados da presente revisão sistemática indicam a presença de evidências que demonstram uma colaboração da pré-medicação com anti-inflamatórios não esteroidais no combate a dor no período de 6 a 8 horas após o tratamento endodôntico.
Objective: The objective of this systematic review was to evaluate the effectiveness of premedication of non-steroidal anti-inflammatory drugs in patients undergoing endodontic treatment, checking the risk and presence of postoperative pain. Method: A search was performed in the Medline databases, with no restriction on the year or language of the publication. Randomized clinical trials that evaluated the efficacy of premedication with non-steroidal anti-inflammatory drugs in reducing postoperative pain were included in this systematic review. A meta-analysis was performed to compare the group of non-steroidal anti-inflammatory drugs and the placebo group between 6 and 8 hours and 24 hours after endodontic treatment. Results: A total of 1809 studies were identified and only eleven studies met the eligibility criteria, seven of which for the meta-analysis. There was a significant difference between the group of anti-inflammatory drugs in relation to the placebo group in the period of 6 to 8 hours after endodontic treatment, however after 24 hours the difference was almost zero in terms of the presence of pain. Conclusion: The results of this systematic review indicate the presence of evidence that demonstrates a collaboration between premedication and non-steroidal anti-inflammatory drugs in the fight against pain in the period of 6 to 8 hours after endodontic treatment.
Objective: The objective of this systematic review was to evaluate the effectiveness of premedication of non-steroidal anti-inflammatory drugs in patients undergoing endodontic treatment, checking the risk and presence of postoperative pain. Method: A search was performed in the Medline databases, with no restriction on the year or language of the publication. Randomized clinical trials that evaluated the efficacy of premedication with non-steroidal anti-inflammatory drugs in reducing postoperative pain were included in this systematic review. A meta-analysis was performed to compare the group of non-steroidal anti-inflammatory drugs and the placebo group between 6 and 8 hours and 24 hours after endodontic treatment. Results: A total of 1809 studies were identified and only eleven studies met the eligibility criteria, seven of which for the meta-analysis. There was a significant difference between the group of anti-inflammatory drugs in relation to the placebo group in the period of 6 to 8 hours after endodontic treatment, however after 24 hours the difference was almost zero in terms of the presence of pain. Conclusion: The results of this systematic review indicate the presence of evidence that demonstrates a collaboration between premedication and non-steroidal anti-inflammatory drugs in the fight against pain in the period of 6 to 8 hours after endodontic treatment.
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Palavras-chave
Endodontia, Anti-Inflamatórios não esteroides, Pré-medicação, Dor, Ensaio clínico controlado, Endodontics