Dihydroisocoumarins produced by Xylaria sp and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla
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The dihydroisocoumarin (3R, 4R)-3,4-dihydro-4,6-dihydroxy-3-methyl-1-oxo-1H-isochromene-5-carboxylic acid (1) was isolated from Xylaria sp., a fungus associated with Piper aduncum (Piperaceae). Additionally, two known compounds, (R)-7-hydroxymellein (2) and (3R, 4R)-4,7-dihydroxymellein (3), were isolated from Penicillium sp. associated to Alibertia macrophylla (Rubiaceae). The structures of all compounds were elucidated by analysis of spectroscopic data. The dihydrocoumarin derivatives 1-3 showed antifungal and acetylcholinesterase (AChE) inhibitory activities in vitro. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
How to cite this document
Oliveira, Camila M. et al. Dihydroisocoumarins produced by Xylaria sp and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla. Phytochemistry Letters. Amsterdam: Elsevier B.V., v. 4, n. 2, p. 93-96, 2011. Available at: <http://hdl.handle.net/11449/26027>.
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