Publicação: EFFECT OF FENCAMFAMINE ON AVOIDANCE PERFORMANCES OF RATS
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Associação Brasileira de Divulgação Científica (ABRADIC)
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Artigo
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Resumo
The effects of fencamfamine (1.0 and 5.0 mg/kg, ip, single dose) on an inhibitory task were studied in rats (N = 15 per group). Post-training treatment with fencamfamine (1.0 mg/kg) significantly increased avoidance latency from 23 +/- 3 to 146 +/- 28 and 170 +/- 33 s for training day 1 and day 7, respectively, indicating an enhancement of retention. However, retention was significantly reduced with a high dose of fencamfamine (5.0 mg/kg). These results demonstrate that fencamfamine caused a reproducible dose-related increase and reduction in avoidance latency.
Descrição
Palavras-chave
FENCAMFAMINE, INHIBITORY AVOIDANCE, COGNITION
Idioma
Inglês
Como citar
Brazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 24, n. 3, p. 307-309, 1991.
