ONE-POT SYNTHESIS OF ISOQUINUCLIDINE DERIVATIVES THROUGH MULTICOMPONENT AZA-DIELS-ALDER REACTIONS PROMOTED BY NIOBIUM PENTAETHOXIDE

dc.contributor.authorSacoman Torquato da Silva, Bruno Henrique [UNESP]
dc.contributor.authorLuiz Carlos da Silva-Filho, Lucas Michelao Martinsand [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T15:29:11Z
dc.date.available2018-11-26T15:29:11Z
dc.date.issued2015-01-01
dc.description.abstractThe bicyclic isoquinuclidine system can be found in many natural products and has several pharmacological properties. In this paper is described an one-pot sysnthesis of Isoquinuclidine derivatives through multicomponent aza-Diels-Alder reactions between aniline derivatives, benzaldehyde and 2-cyclohexenone, promoted by niobium pentaethoxide under mild conditions, affording the expected products in high yields.en
dc.description.affiliationSao Paulo State Univ UNESP, Lab Organ Synth & Proc LaSOP, BR-17033360 Bauru, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Lab Organ Synth & Proc LaSOP, BR-17033360 Bauru, SP, Brazil
dc.format.extent431-442
dc.identifier.citationHeterocyclic Letters. Jaipur: Raman Publ, v. 5, n. 3, p. 431-442, 2015.
dc.identifier.issn2231-3087
dc.identifier.urihttp://hdl.handle.net/11449/158785
dc.identifier.wosWOS:000373301800017
dc.language.isoeng
dc.publisherRaman Publ
dc.relation.ispartofHeterocyclic Letters
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectIsoquinuclidine derivatives
dc.subjectNiobium pentaethoxide
dc.subjectmulticomponent reaction
dc.subjectaza-Diels-Alder
dc.subjectLewis acid
dc.titleONE-POT SYNTHESIS OF ISOQUINUCLIDINE DERIVATIVES THROUGH MULTICOMPONENT AZA-DIELS-ALDER REACTIONS PROMOTED BY NIOBIUM PENTAETHOXIDEen
dc.typeArtigo
dcterms.rightsHolderRaman Publ

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