Case Report: Treatment of Chromoblastomycosis with Combinations including Acitretin: A Report of Two Cases

dc.contributor.authorBelda, Walter
dc.contributor.authorCriado, Paulo Ricardo
dc.contributor.authorPassero, Luiz Felipe Domingues [UNESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionFundação Universitária do ABC (FUABC)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-25T11:02:55Z
dc.date.available2021-06-25T11:02:55Z
dc.date.issued2020-11-01
dc.description.abstractChromoblastomycosis is a cutaneous fungal infection caused by dematiaceous fungi that belong to the order Chaetothyriales and family Herpotrichiellaceae. This infection is prevalent in tropical and subtropical areas and has been designated as a neglected tropical disease according to the WHO. Chromoblastomycosis infection is difficult to treat, and there are limited therapeutic options, making urgent the characterization of new medicines or approaches to treat such infection. In the present case report, two patients with extensive chromoblastomycosis lesions were treated with the combination of itraconazole, acitretin, and imiquimod. In the fourth month of treatment, both patients showed improvement of verrucous plates, suggesting that acitretin combined with drugs already used in chromoblastomycosis therapy can decrease the time of treatment, improving patient’s quality of life.en
dc.description.affiliationDermatology Department Clinics Hospital Medical School University of São Paulo
dc.description.affiliationLaboratory of Pathology of Infectious Diseases Medical School University of São Paulo
dc.description.affiliationABC School of Medicine Fundação Universitária do ABC (FUABC)
dc.description.affiliationInstitute of Biosciences São Paulo State University (UNESP)
dc.description.affiliationInstitute for Advanced Studies of Ocean São Paulo State University (UNESP)
dc.description.affiliationUnespInstitute of Biosciences São Paulo State University (UNESP)
dc.description.affiliationUnespInstitute for Advanced Studies of Ocean São Paulo State University (UNESP)
dc.format.extent1852-1854
dc.identifierhttp://dx.doi.org/10.4269/ajtmh.20-0471
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene, v. 103, n. 5, p. 1852-1854, 2020.
dc.identifier.doi10.4269/ajtmh.20-0471
dc.identifier.issn1476-1645
dc.identifier.issn0002-9637
dc.identifier.scopus2-s2.0-85096147285
dc.identifier.urihttp://hdl.handle.net/11449/207896
dc.language.isoeng
dc.relation.ispartofAmerican Journal of Tropical Medicine and Hygiene
dc.sourceScopus
dc.titleCase Report: Treatment of Chromoblastomycosis with Combinations including Acitretin: A Report of Two Casesen
dc.typeArtigo

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