The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors

dc.contributor.authorArruda, Maria Sueli Parreira de [UNESP]
dc.contributor.authorCorrea, Mara Adriana [UNESP]
dc.contributor.authorVenturini, James [UNESP]
dc.contributor.authorFélix, Maira Camila [UNESP]
dc.contributor.authorDe Rosis, Ana Maria Bormio [UNESP]
dc.contributor.authorGalhiane, Mario Sergio [UNESP]
dc.contributor.authorChierice, Gilberto Orivaldo
dc.contributor.authorCosta, Maria Renata Sales Nogueira
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionInsituto Lauro de Sousa Lima
dc.date.accessioned2014-05-20T13:25:44Z
dc.date.available2014-05-20T13:25:44Z
dc.date.issued2011-12-01
dc.description.abstractThe aim of the present study was to examine the effect of a diet rich in synthetic PEtn on the metabolism macrophages of tumor-bearing mice. The results demonstrated that PEtn increased the animals' survival time. In addition, the treated animals released smaller amounts of hydrogen peroxide (H2O2) and nitric oxide (NO) than the non-treated animals, particularly after day 14. From the results it could be concluded that H2O2 and NO were important in the modulation of neoplastic growth, and pointed to a promising role of PEtn in the control of human neoplasms.en
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Ciências Departamento de Ciências Biológicas
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Ciências Departamento de Química
dc.description.affiliationUniversidade de São Paulo Departamento de Química e Física Molecular
dc.description.affiliationInsituto Lauro de Sousa Lima
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Ciências Departamento de Ciências Biológicas
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Ciências Departamento de Química
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)
dc.format.extent1203-1210
dc.identifierhttp://dx.doi.org/10.1590/S1516-89132011000600016
dc.identifier.citationBrazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 54, n. 6, p. 1203-1210, 2011.
dc.identifier.doi10.1590/S1516-89132011000600016
dc.identifier.fileS1516-89132011000600016.pdf
dc.identifier.issn1516-8913
dc.identifier.lattes0711431566503022
dc.identifier.lattes3612277056838097
dc.identifier.scieloS1516-89132011000600016
dc.identifier.urihttp://hdl.handle.net/11449/8183
dc.identifier.wosWOS:000298106300016
dc.language.isoeng
dc.publisherBrazilian Archives of Biology and Technology
dc.relation.ispartofBrazilian Archives of Biology and Technology
dc.relation.ispartofjcr0.676
dc.relation.ispartofsjr0,281
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectPhosphoethanolamineen
dc.subjectEhrlich tumoren
dc.subjectnitric oxideen
dc.subjecthydrogen peroxideen
dc.subjectlipidsen
dc.titleThe effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumorsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/babt/paboutj.htm
unesp.author.lattes0711431566503022
unesp.author.lattes3612277056838097
unesp.author.orcid0000-0003-4985-3330[2]
unesp.author.orcid0000-0003-0035-2439[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências, Baurupt
unesp.departmentCiências Biológicas - FCpt
unesp.departmentQuímica - FCpt

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