Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa

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dc.contributor.authorSerrano, Maria Amélia Rodrigues [UNESP]
dc.contributor.authorDe Luca Batista, Andrea Nastri [UNESP]
dc.contributor.authorDa Silva Bolzani, Vanderlan [UNESP]
dc.contributor.authorDe Ávila Santos, Luciana [UNESP]
dc.contributor.authorDe Campos Nogueira, Paulo José [UNESP]
dc.contributor.authorNunes-De-Souza, Ricardo Luiz [UNESP]
dc.contributor.authorLatif, Abdul
dc.contributor.authorArfan, Mohammad
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Peshawar
dc.date.accessioned2022-04-29T08:48:43Z
dc.date.available2022-04-29T08:48:43Z
dc.date.issued2011-08-05
dc.description.abstractTwo alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).en
dc.description.affiliationInstituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SP
dc.description.affiliationFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SP
dc.description.affiliationInstitute of Chemical Sciences University of Peshawar, Peshawar
dc.description.affiliationUnespInstituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SP
dc.description.affiliationUnespFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SP
dc.format.extent808-811
dc.identifier.citationQuimica Nova, v. 34, n. 5, p. 808-811, 2011.
dc.identifier.issn0100-4042
dc.identifier.issn1678-7064
dc.identifier.scopus2-s2.0-79960993898
dc.identifier.urihttp://hdl.handle.net/11449/232020
dc.language.isoeng
dc.relation.ispartofQuimica Nova
dc.sourceScopus
dc.subjectAnxyolitic activity
dc.subjectE. suberosa
dc.subjectErythrinian alkaloids
dc.titleAnxiolytic-like effects of erythrinian alkaloids from erythrina suberosaen
dc.typeArtigo
unesp.departmentPrincípios Ativos Naturais e Toxicologia - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas