Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
| dc.contributor.author | Serrano, Maria Amélia Rodrigues [UNESP] | |
| dc.contributor.author | De Luca Batista, Andrea Nastri [UNESP] | |
| dc.contributor.author | Da Silva Bolzani, Vanderlan [UNESP] | |
| dc.contributor.author | De Ávila Santos, Luciana [UNESP] | |
| dc.contributor.author | De Campos Nogueira, Paulo José [UNESP] | |
| dc.contributor.author | Nunes-De-Souza, Ricardo Luiz [UNESP] | |
| dc.contributor.author | Latif, Abdul | |
| dc.contributor.author | Arfan, Mohammad | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.contributor.institution | University of Peshawar | |
| dc.date.accessioned | 2022-04-29T08:48:43Z | |
| dc.date.available | 2022-04-29T08:48:43Z | |
| dc.date.issued | 2011-08-05 | |
| dc.description.abstract | Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM). | en |
| dc.description.affiliation | Instituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SP | |
| dc.description.affiliation | Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SP | |
| dc.description.affiliation | Institute of Chemical Sciences University of Peshawar, Peshawar | |
| dc.description.affiliationUnesp | Instituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SP | |
| dc.description.affiliationUnesp | Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SP | |
| dc.format.extent | 808-811 | |
| dc.identifier.citation | Quimica Nova, v. 34, n. 5, p. 808-811, 2011. | |
| dc.identifier.issn | 0100-4042 | |
| dc.identifier.issn | 1678-7064 | |
| dc.identifier.scopus | 2-s2.0-79960993898 | |
| dc.identifier.uri | http://hdl.handle.net/11449/232020 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Quimica Nova | |
| dc.source | Scopus | |
| dc.subject | Anxyolitic activity | |
| dc.subject | E. suberosa | |
| dc.subject | Erythrinian alkaloids | |
| dc.title | Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa | en |
| dc.type | Artigo | |
| unesp.department | Princípios Ativos Naturais e Toxicologia - FCF | pt |