Gelatinous polyethylene in the treatment of the anophthalmic cavity
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Data
2002-08-23
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Coorientador
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Resumo
PURPOSE: Gelatinous polyethylene (GP) has been used as an orbital implant to evaluate volume maintenance and tissue reaction in the anophthalmic socket in a rabbit model. METHODS: Twenty-eight Norfolk white rabbits underwent unilateral evisceration with placement of 2ml GP (GP group - 16 animals) or 2ml 0.9% sodium chloride solution (Control group - 12 animals). Animal behavior, postoperative tissue response and socket conditions were evaluated. The animals were sacrificed at 7, 15, 30 and 60 days after the surgery and the bulbs were enucleated; volume maintenance and histopathological evaluation were done in the enucleated bulbs. The results were submitted to statistical analysis. RESULTS: All animals showed normal behavior. The orbital volume maintenance was better in the GP group. Histopathology in the GP animals showed mild tissue inflammation throughout the evaluation period and a thin pseudocapsule formation surrounding the orbital implant material. CONCLUSION: The clinical findings, good orbital volume maintenance and mild inflammatory tissue response make GP a good choice to replace the lack of volume in anophthalmic socket reconstruction.
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Anophthalmic socket , Gelatinous polyethylene , Histopathology , Orbital volume , Rabbits , Socket reconstruction , polyethylene , sodium chloride , animal experiment , animal tissue , anophthalmia , controlled study , enucleation , evisceration , gel , histopathology , implant , inflammation , nonhuman , rabbit , statistical analysis , Animal , Biocompatible Materials , Comparative Study , Eye Enucleation , Gelatin , Models, Animal , Orbit , Orbital Implants , Polyethylenes , Prosthesis Implantation , Random Allocation , Treatment Outcome
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Inglês
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Orbit, v. 21, n. 3, p. 189-193, 2002.