Non-aqueous Titration of Gatifloxacin in Pharmaceutical Formulations using Perchloric Acid

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dc.contributor.authorMarona, Hérida R. N. [UNESP]
dc.contributor.authorLopes, Cristiani C. G. O. [UNESP]
dc.contributor.authorCardoso, Simone G.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Sergipe (UFS)
dc.date.accessioned2014-05-27T11:20:55Z
dc.date.available2014-05-27T11:20:55Z
dc.date.issued2003-10-01
dc.description.abstractAn inexpensive, simple, precise and rapid method for the determination of fluoroquinolone gatifloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a non-aqueous medium in glacial acetic acid with 0.1 M perchloric acid. The method validation yielded good results and included the precision, recovery and accuracy. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay.en
dc.description.affiliationProg. Pos-Graduacao Cie. Farmaceut. FCF UNESP, Araraquara, SP
dc.description.affiliationCentro de Ciencias da Saude UFSM, Santa Maria, RS
dc.description.affiliationUnespProg. Pos-Graduacao Cie. Farmaceut. FCF UNESP, Araraquara, SP
dc.format.extent339-342
dc.identifierhttp://www.latamjpharm.org/trabajos/22/4/LAJOP_22_4_2_1_BME2CBRX6V.pdf
dc.identifier.citationActa Farmaceutica Bonaerense, v. 22, n. 4, p. 339-342, 2003.
dc.identifier.issn0326-2383
dc.identifier.scopus2-s2.0-0347123113
dc.identifier.urihttp://hdl.handle.net/11449/67436
dc.language.isoeng
dc.relation.ispartofActa Farmaceutica Bonaerense
dc.relation.ispartofjcr0.401
dc.relation.ispartofsjr0,152
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectFluoroquinolone
dc.subjectGatifloxacin
dc.subjectNon-aqueous titration
dc.subjectPharmaceutical analysis
dc.subjectacetic acid
dc.subjectcrystal violet
dc.subjectexcipient
dc.subjectgatifloxacin
dc.subjectperchloric acid
dc.subjectquinoline derived antiinfective agent
dc.subjectaccuracy
dc.subjectanalytic method
dc.subjectdrug determination
dc.subjectdrug formulation
dc.subjectquantitative assay
dc.subjecttablet
dc.subjecttitrimetry
dc.subjectvalidation process
dc.subjectweight
dc.titleNon-aqueous Titration of Gatifloxacin in Pharmaceutical Formulations using Perchloric Aciden
dc.typeArtigo
dcterms.licensehttp://www.latamjpharm.org/

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