Publicação:
Ultrastructural and morphometric aspects of ageing in the retinal capillaries of rats

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dc.contributor.authorSchellini, Silvana Artioli [UNESP]
dc.contributor.authorGregório, E. A. [UNESP]
dc.contributor.authorPadovani, Carlos Roberto [UNESP]
dc.contributor.authorSpadella, César Tadeu [UNESP]
dc.contributor.authorMoraes-Silva, M. A. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:18:13Z
dc.date.available2014-05-27T11:18:13Z
dc.date.issued1997-04-01
dc.description.abstractAge-related morphological, ultrastructural and morphometric changes in the capillaries of the superficial and deep plexuses of the rat retina were studied in animals aged from 3 to 15 months. Our results suggest that age-related morphological alterations start occurring in the retina of rats at about 12 months of age. Increased glycogen deposits, pinocytotic vesicles, residual bodies and cell debris were observed in both the endothelial and pericytic cells of 12- and 15-month-old animals. In addition, heterogeneous osmiophilic accumulations, electron-transparent spaces were observed in the basement membrane as well as projections of the basement membrane towards the neighboring cells. Morphometric examination of the two vascular plexuses studied did not show differences in the area of the endothelial or pericytic cells, basement membrane or vascular lumen between rats of different ages.en
dc.description.affiliationDepartment of Ophthalmology Medical School UNESP, Botucatu, SP
dc.description.affiliationDepartment of Morphology Institute of Biosciences UNESP, Botucatu, SP
dc.description.affiliationDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, SP
dc.description.affiliationDept. of Surgery and Orthopedics Medical School UNESP, Botucatu, SP
dc.description.affiliationDepartamento de Oftalmologia Otorrinolaringologia Cir. Cabeca P. UNESP, CEP 18618-000 Rubião Junior, Botucatu, SP
dc.description.affiliationUnespDepartment of Ophthalmology Medical School UNESP, Botucatu, SP
dc.description.affiliationUnespDepartment of Morphology Institute of Biosciences UNESP, Botucatu, SP
dc.description.affiliationUnespDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, SP
dc.description.affiliationUnespDept. of Surgery and Orthopedics Medical School UNESP, Botucatu, SP
dc.description.affiliationUnespDepartamento de Oftalmologia Otorrinolaringologia Cir. Cabeca P. UNESP, CEP 18618-000 Rubião Junior, Botucatu, SP
dc.format.extent275-280
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/9165721
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology, v. 29, n. 2, p. 275-280, 1997.
dc.identifier.issn1122-9497
dc.identifier.lattes6223012281302736
dc.identifier.lattes9420249100835492
dc.identifier.lattes8727897080522289
dc.identifier.scopus2-s2.0-0031114227
dc.identifier.urihttp://hdl.handle.net/11449/65084
dc.identifier.wosWOS:A1997WX12600015
dc.language.isoeng
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAgeing
dc.subjectMorphometry
dc.subjectRat
dc.subjectRetinal vessels
dc.subjectUltrastructure
dc.subjectaging
dc.subjectanimal
dc.subjectcapillary
dc.subjectelectron microscopy
dc.subjectgrowth, development and aging
dc.subjectmuscle development
dc.subjectrat
dc.subjectretina blood vessel
dc.subjectultrastructure
dc.subjectvascular endothelium
dc.subjectvascular smooth muscle
dc.subjectWistar rat
dc.subjectAging
dc.subjectAnimals
dc.subjectCapillaries
dc.subjectEndothelium, Vascular
dc.subjectMicroscopy, Electron
dc.subjectMuscle Development
dc.subjectMuscle, Smooth, Vascular
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectRetinal Vessels
dc.titleUltrastructural and morphometric aspects of ageing in the retinal capillaries of ratsen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes6223012281302736
unesp.author.lattes9420249100835492
unesp.author.lattes8727897080522289[3]
unesp.author.orcid0000-0002-7719-9682[3]
unesp.author.orcid0000-0002-6938-1230[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentCirurgia e Ortopedia - FMBpt
unesp.departmentOftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - FMBpt
unesp.departmentBioestatística - IBBpt
unesp.departmentMorfologia - IBBpt

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Botucatu - FMB - Faculdade de Medicina
Botucatu - IBB - Instituto de Biociências