Learning curve for the laparoscopy-guided kidney biopsy procedure in small corpses of dogs and pigs

dc.contributor.authorMaia, Suellen Rodrigues [UNESP]
dc.contributor.authorMendes, Pamela Almerinda
dc.contributor.authorda Câmara Barros, Felipe Farias Pereira
dc.contributor.authorAyer, Ilan Munhoz
dc.contributor.authorRamos, Salvador Boccaletti
dc.contributor.authorVacari, Alessandra Marieeli
dc.contributor.authorLucera, Tiago Machado Carneiro
dc.contributor.authorMurakami, Vanessa Yurika
dc.contributor.authorde Carvalho, Leonardo Lamarca
dc.contributor.authorBernardino, Pedro Negri
dc.contributor.authorGouvêa, Fernanda Nastri
dc.contributor.authorBorin-Crivellenti, Sofia
dc.contributor.authorCrivellenti, Leandro Zuccolotto
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Franca (UNIFRAN)
dc.contributor.institutionFederal Rural University of Rio de Janeiro (UFRRJ)
dc.contributor.institutionUNA—Academic Center
dc.contributor.institutionVeterinary Teaching Hospital of University of Franca (UNIFRAN)
dc.contributor.institutionUniversity of California Davis (UC DAVIS)
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.description.abstractThe use of renal biopsy through laparoscopy is increasingly present both in human and veterinary medicine. However, both techniques require skill and training to make the operator capable to do it. The learning curve allows the quantitative and qualitative assessment of the number of attempts and minimum time for the surgical procedure. The objective included establish the learning curve for laparoscopy-guided kidney biopsy procedures in dog and pig corpses. Six dogs and six pigs corpses weighing less than 10 kg were used for this study. All corpses underwent kidney biopsy performed through laparoscopy. Twenty-four operators, two per animal, performed 20 renal biopsies each (10 for each kidney), with 480 collection-procedures in total. Duration and difficulty of the procedure and the biopsy sample quality were evaluated and statistical analysis was performed using a mixed regression model with a random effect of individuals and multivariate analysis of data. There were 91.5% of the samples that were adequate for evaluation. There was no significant difference in the number of glomeruli or cortex percentage considering the attempts in either species, demonstrating the operator’s ability since first collection. Swine samples showed higher amounts of renal cortex than canine samples. The procedure duration was shorter as more attempts were performed in dogs and pigs. From the fourth repetition, the professional reached a plateau for the variable related to ‘collection’, and from the second, the professional presented uniform duration for ‘sample storage’. Operators of the swine model acquired more agility than the dog ones. The variable ‘difficulty’ decreased as more repetitions were performed, reaching a plateau in the sixth attempt. Seven renal biopsies laparoscopy-guided are required for an operator to be considered ‘capable’ to perform the procedure in the referred species included. The learning curve for image-guided kidney biopsy procedures improves the implementation of this technique and benefits patients that undergo this procedure.en
dc.description.affiliationDepartment of Veterinary Clinics School of Veterinary Medicine and Animal Science São Paulo State University (UNESP), São Paulo
dc.description.affiliationUniversity of Franca (UNIFRAN), São Paulo
dc.description.affiliationDepartment of Veterinary Medicine and Surgery Federal Rural University of Rio de Janeiro (UFRRJ), Seropédica
dc.description.affiliationDepartment of Animal Science UNA—Academic Center, Pouso Alegre, Minas Gerais
dc.description.affiliationHealth Promotion Graduate Program University of Franca (UNIFRAN), Franca
dc.description.affiliationAnimal Science Graduate Program Veterinary Teaching Hospital of University of Franca (UNIFRAN), Franca, São Paulo
dc.description.affiliationGlobal Study Program University of California Davis (UC DAVIS)
dc.description.affiliationGraduate Program in Veterinary Science (PPGCV) College of Veterinary Medicine (FAMEV) Federal University of Uberlândia (UFU), Uberlândia, Minas Gerais
dc.description.affiliationUnespDepartment of Veterinary Clinics School of Veterinary Medicine and Animal Science São Paulo State University (UNESP), São Paulo
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: #2017/ 25458-0
dc.identifier.citationPLoS ONE, v. 16, n. 9 September 2021, 2021.
dc.relation.ispartofPLoS ONE
dc.titleLearning curve for the laparoscopy-guided kidney biopsy procedure in small corpses of dogs and pigsen