Publicação:
Chromosome aberrations in lymphocyte cultures from paracoccidioidomycosis patients

Página do item simplificado
dc.contributor.authorFreire-Maia, D. V. [UNESP]
dc.contributor.authorGarcia, M. G. [UNESP]
dc.contributor.authorMendes, R. P. [UNESP]
dc.contributor.authorMarques, S. A. [UNESP]
dc.contributor.authorCuri, P. R. [UNESP]
dc.contributor.authorSouza, L. R. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:17:57Z
dc.date.available2014-05-27T11:17:57Z
dc.date.issued1994-07-21
dc.description.abstractBlood cell lymphocyte chromosomes from untreated (UT) and clinically-cured (CC) patients with paracoccidioidomycosis and from healthy (control) people (CO) were studied. The frequency of aneuploid cells in the UT patients was higher than in the CC and CO individuals. The frequency of metaphase cells with premature centromere division was significantly higher in the UT than in the CC and CO group. No structural aberration and no statistically significant difference in the frequency of polyploidy was observed in the three groups studied. Our findings are indicative of an aneugenic (aneuploidy-inducing) action of infection by Paracoccidioides brasiliensis.en
dc.description.affiliationUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,BOTUCATU MED SCH,DEPT DERMATOL & INFECT DIS,BR-18618000 BOTUCATU,SP,BRAZIL
dc.description.affiliationUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,SCH VET MED & ZOOTECH,STAT & COMPUTAT SERV,BR-18618000 BOTUCATU,SP,BRAZIL
dc.description.affiliationUnespDepartment of Genetics Institute of Biosciences UNESP, 18618-000 Botucatu, Sao Paulo
dc.format.extent199-203
dc.identifierhttp://dx.doi.org/10.1080/02681219480000261
dc.identifier.citationJournal of Medical and Veterinary Mycology, v. 32, n. 3, p. 199-203, 1994.
dc.identifier.doi10.1080/02681219480000261
dc.identifier.issn0268-1218
dc.identifier.lattes8789480458377552
dc.identifier.scopus2-s2.0-0028064743
dc.identifier.urihttp://hdl.handle.net/11449/132306
dc.identifier.wosWOS:A1994NU15600005
dc.language.isoeng
dc.publisherBlackwell Science
dc.relation.ispartofJournal of Medical and Veterinary Mycology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAdult
dc.subjectAneuploidy
dc.subjectChromosome aberration
dc.subjectControlled study
dc.subjectHuman
dc.subjectHuman cell
dc.subjectLymphocyte culture
dc.subjectMajor clinical study
dc.subjectMale
dc.subjectMetaphase
dc.subjectMycosis
dc.subjectPolyploidy
dc.subjectSouth american blastomycosis
dc.subjectAdult
dc.subjectChromosome Aberrations
dc.subjectFemale
dc.subjectHuman
dc.subjectLymphocytes
dc.subjectMale
dc.subjectMetaphase
dc.subjectMiddle Age
dc.subjectParacoccidioidomycosis
dc.subjectPloidies
dc.subjectSupport, Non-U.S. Gov't
dc.titleChromosome aberrations in lymphocyte cultures from paracoccidioidomycosis patientsen
dc.typeArtigo
dcterms.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dcterms.rightsHolderBlackwell Science Ltd
dspace.entity.typePublication
unesp.author.lattes8789480458377552
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentDermatologia e Radioterapia - FMBpt
unesp.departmentGenética - IBBpt

Arquivos

Coleções

Botucatu - FMB - Faculdade de Medicina
Botucatu - IBB - Instituto de Biociências